Impact of lung expansion therapy using positive end-expiratory pressure in mechanically ventilated patients submitted to coronary artery bypass grafting
Rev. bras. cir. cardiovasc
; 34(6): 699-703, Nov.-Dec. 2019. tab
Article
in English
| LILACS
| ID: biblio-1057490
Responsible library:
BR1.1
ABSTRACT
Abstract Objective:
To evaluate the impact of different levels of positive end-expiratory pressure (PEEP) on gas exchange in patients undergoing coronary artery bypass grafting (CABG).Methods:
A randomized clinical trial was conducted with patients undergoing CABG surgery. Patients were randomized into three groups Group 10, PEEP of 10 cmH2O; Group 12, PEEP of 12 cmH2O; and Group 15, PEEP of 15 cmH2O. After the randomization, all patients underwent gas analysis at three moments (1) before lung expansion therapy (LET); (2) 30 minutes after LET; and (3) one hour after extubation.Results:
Sixty-six patients were studied, of which 61.7% were men, with mean age of 64 ± 8.9 years. Patients allocated to Group 15 showed a significant improvement in gas exchange comparing pre- and post-expansion values (239±21 vs. 301±19, P<0,001) and the increase was maintained after extubation (278±26). Despite the use of high levels of PEEP, no significant hemodynamic change was evidenced.Conclusion:
It is concluded that high levels of PEEP (15 cmH2O) are beneficial for the improvement of gas exchange in patients undergoing CABG.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Coronary Artery Bypass
/
Positive-Pressure Respiration
Type of study:
Controlled clinical trial
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
English
Journal:
Rev. bras. cir. cardiovasc
Journal subject:
Cardiology
/
CIRURGIA GERAL
Year:
2019
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Escola Bahiana de Medicina e Saúde Pública (Bahiana)/BR
/
Instituto Nobre de Cardiologia/BR