Analysis of rabies diagnosis in dogs and cats in the state of São Paulo, Brazil
Arch Virol
; 163(9): 2369-2376, Sept, 2018.
Article
in English
| Sec. Est. Saúde SP, SESSP-IPPROD, Sec. Est. Saúde SP
| ID: biblio-1059784
Responsible library:
BR84.1
Localization: BR84.1
ABSTRACT
The genetic lineage of rabies virus (RABV) associated with dogs has not been found in the state of São Paulo since 1998, and all cases of rabies in domestic animals reported since then have involved the RABV lineage that circulates in bats. As there has been a change in the rabies transmission cycle in cats and dogs, we decided to analyze the tests used to diagnose rabies in these animals in the 15-year period from 2002 to 2016 in the state of São Paulo. During this period, 85,508 central nervous system (CNS) samples from dogs and cats were submitted to the Rabies Diagnosis Section at the Pasteur Institute of São Paulo for testing. All of the samples were tested by the fluorescent antibody test (FAT) and at least one of the following three tests mouse inoculation test (MIT), rabies tissue culture infection test (RTCIT) and reverse transcription polymerase chain reaction (RT-PCR). Of all the samples tested, twenty were positive in at least one of these assays. Four other positive samples were identified at other institutions in the state of São Paulo. Of the twenty samples that tested positive at the Pasteur Institute of São Paulo, nine were tested by FAT, and the results were subsequently confirmed by other techniques; five gave inconclusive results, and therefore, other techniques had to be used as soon as possible in case the samples were positive; and six were negative by FAT and positive by one or more of the following tests...
Full text:
Available
Collection:
National databases
/
Brazil
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
Sec. Est. Saúde SP
/
SESSP-IPPROD
Main subject:
Rabies
/
Rabies virus
/
Animals, Domestic
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Arch Virol
Year:
2018
Document type:
Article