Effect of vaccination and the immunomodulators "bacillus of Calmette-Guerin, Avridine and Propionibacterium acnes" on rabies in mice
Comparative Immunology Microbiology Infectious Diseases
; 21: 305-318, 1998. tab
Article
in English
| Sec. Est. Saúde SP, SESSP-IPPROD, Sec. Est. Saúde SP
| ID: biblio-1062179
Responsible library:
BR84.1
Localization: BR84.1
ABSTRACT
Responses of vaccination and treatment to immunomodulators against rabies in mice were evaluated through macrophage inhibition factor (MIF), intra-pad inoculation (IPI) and serum neutralization (SN) tests and by the detection of g-interferon (IFN-g). Onco-BCG, Avridine and Propionibacterium acnes were administered to groups of mice. Higher survival rates were found in animals treated with P. acnes. Lower levels of IFN-g were observed in the groups of infected and vaccinated mice. The IPI was not effective on detecting the response of delayed-type hypersensitivity. Vaccine induced in the infected animals a more intense response to MIF reaction.
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Collection:
National databases
/
Brazil
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Neglected Diseases
/
Zoonoses
Database:
Sec. Est. Saúde SP
/
SESSP-IPPROD
Main subject:
Propionibacterium acnes
/
Rabies
/
BCG Vaccine
/
Adjuvants, Immunologic
/
Vaccination
Limits:
Animals
Language:
English
Journal:
Comparative Immunology Microbiology Infectious Diseases
Year:
1998
Document type:
Article