MortalitY in caRdIAc surgery (MYRIAD): A randomizeD controlled trial of volatile anesthetics. Rationale and design
Contemp Clin Trials
; 59: 38-43, 2017. tab
Article
in English
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1062268
Responsible library:
BR79.1
Localization: BR79.1
ABSTRACT
Objective:
There is initial evidence that the use of volatile anesthetics can reduce the postoperative release of cardiac troponin I, the need for inotropic support, and the number of patients requiring prolonged hospitalization following coronary artery bypass graft (CABG) surgery. Nevertheless,small Randomized Controlled Trials have failed to demonstrate a survival advantage. Thus, whethervolatile anesthetics improve the postoperative outcome of cardiac surgical patients remains uncertain. An adequately powered randomized controlled trial appears desirable.Design:
Single blinded, international, multicenter randomized controlled trial with 11 allocation ratio.Setting:
Tertiary and University hospitals.
Full text:
Available
Collection:
National databases
/
Brazil
Database:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Main subject:
Mortality
/
Drug-Related Side Effects and Adverse Reactions
/
Anesthesia
Type of study:
Controlled clinical trial
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Contemp Clin Trials
Year:
2017
Document type:
Article
Institution/Affiliation country:
1st Affiliated Hospital of Fourth Military University/CN
/
Academician EN Meshalkin Novosibirsk StateBudget Research Institute of Circulation Pathology/RU
/
Astrakhan Federal Centre for CardiacSurgery/RU
/
Azienda Ospedaliera Spedali Civili/IT
/
Azienda Ospedaliero-Universitaria Pisana/IT
/
Azienda ospedaliera San Camillo Forlanini/IT
/
Beijing Anzhen Hospital/CN
/
Cardiovascular Institute `Dedinje'/RS
/
City Clinic Burgas/BG
/
Dante Pazzanese Institute of Cardiology/BR