Enhancing effect of a protein from Lonomia obliqua hemolymph on recombinant protein production
Cytotechnology
; 57(1): 83-91, 2008.
Article
in English
| Sec. Est. Saúde SP, SESSP-IBPROD, Sec. Est. Saúde SP, SESSP-IBACERVO
| ID: biblio-1062331
Responsible library:
BR78.1
Localization: BR78.1
ABSTRACT
Abstract Gene expression in animal cells allows large scale production of proteins used for either structure and function studies or therapeutic purposes. Maximizing recombinant protein production is necessary to optimize cell growth and protein expression. Some studies have demonstrated the presence of pharmacologically active substances in insect hemolymph. In this work, we have identified and purified a protein from Lonomia obliqua hemolymph able to increase the production of the rabies virus glycoprotein, expressed in Drosophila melanogaster S2 cells, by about 59%.
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Collection:
National databases
/
Brazil
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
Sec. Est. Saúde SP
/
SESSP-IBACERVO
/
SESSP-IBPROD
Main subject:
Rabies virus
/
Insect Proteins
Limits:
Animals
Language:
English
Journal:
Cytotechnology
Year:
2008
Document type:
Article
Institution/Affiliation country:
Instituto Butantan/BR