Association between transcatheter aortic valve replacement and subsequent infective endocarditis and in-hospital death
JAMA
; 316(10): 1083-1092, 2016.
Article
in English
| Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP
| ID: biblio-1064090
Responsible library:
BR79.1
Localization: BR79.1
ABSTRACT
IMPORTANCE Limited data exist on clinical characteristics and outcomes of patients who had infective endocarditis after undergoing transcatheter aortic valve replacement (TAVR). OBJECTIVE:
To determine the associated factors, clinical characteristics, and outcomes of patients who had infective endocarditis after TAVR. DESIGN, SETTING, ANDPARTICIPANTS:
The Infectious Endocarditis after TAVR International Registry included patients with definite infective endocarditis after TAVR from 47 centers from Europe, North America, and South America between June 2005 and October 2015. EXPOSURE Transcatheter aortic valve replacement for incidence of infective endocarditis and infective endocarditis for in-hospital mortality. MAIN OUTCOMES ANDMEASURES:
Infective endocarditis and in-hospital mortality after infective endocarditis.RESULTS:
A total of 250 cases of infective endocarditis occurred in 20 006 patients after TAVR (incidence, 1.1% per person-year; 95% CI, 1.1%-1.4%; median age, 80 years; 64% men). Median time from TAVR to infective endocarditis was 5.3 months (interquartile range [IQR], 1.5-13.4 months). The characteristics associated with higher risk of progressing to infective endocarditis after TAVR was younger age (78.9 years vs 81.8 years; hazard ratio [HR], 0.97 per year; 95% CI, 0.94-0.99), male sex (62.0% vs 49.7%; HR, 1.69; 95% CI, 1.13-2.52), diabetes mellitus (41.7% vs 30.0%; HR, 1.52; 95% CI, 1.02-2.29), and moderate to severe aortic regurgitation (22.4% vs 14.7%; HR, 2.05; 95% CI, 1.28-3.28). Health care-associated infective endocarditis was present in 52.8% (95% CI, 46.6%-59.0%) of patients...
Search on Google
Collection:
National databases
/
Brazil
Database:
Sec. Est. Saúde SP
/
SESSP-IDPCPROD
Main subject:
Endocarditis
/
Endocarditis, Bacterial
/
Transcatheter Aortic Valve Replacement
Type of study:
Risk factors
Language:
English
Journal:
JAMA
Year:
2016
Document type:
Article
Institution/Affiliation country:
Azienda Ospedaliera, S. Croce e Carle Cuneo/IT
/
Bern University Hospital (on behalf of Swiss TAVI Registry Centres)/CH
/
Bichat Hôpital/FR
/
Bichat Hôpital, AP-HP, University Paris Diderot/FR
/
Cedars-Sinai Heart Institute/US
/
Centre Hospitalier Universitaire de Rennes/FR
/
Centre Hospitalier de l'Universite de Montreal/CA
/
Centro Cardiologico Monzino/IT
/
Cleveland Clinic/US
/
Clinique Pasteur/FR