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One-month therapy with simvastatin restores endothelial function in hypercholesterolemic children and adolescents
Ferreira, Waldinai Pereira; Bertolami, Marcelo Chiara; Santos, Simone Nascimento; Barros, Marcos Roberto AC; Barretto, Rodrigo Bellio de Matos; Pontes Jr, Sérgio Cunha; Fonseca, Francisco Hermann; Carvalho, Antonio Carlos.
Affiliation
  • Ferreira, Waldinai Pereira; Instituto Dante Pazzanese de Cardiologia. BR
  • Bertolami, Marcelo Chiara; Instituto Dante Pazzanese de Cardiologia. BR
  • Santos, Simone Nascimento; Instituto Dante Pazzanese de Cardiologia. BR
  • Barros, Marcos Roberto AC; Instituto Dante Pazzanese de Cardiologia. BR
  • Barretto, Rodrigo Bellio de Matos; Instituto Dante Pazzanese de Cardiologia. BR
  • Pontes Jr, Sérgio Cunha; Instituto Dante Pazzanese de Cardiologia. BR
  • Fonseca, Francisco Hermann; Instituto Dante Pazzanese de Cardiologia. BR
  • Carvalho, Antonio Carlos; Instituto Dante Pazzanese de Cardiologia. BR
Pediatr Cardiol ; 28(01): 8-13, 25 de janeiro de 2007.
Article in English | Sec. Est. Saúde SP, SESSP-IDPCPROD, Sec. Est. Saúde SP | ID: biblio-1065180
Responsible library: BR79.1
Localization: BR79.1
ABSTRACT
Simvastatin has been shown to restore endothelial function in children with familial hypercolesterolemia after 28 weeks of treatment. The aim of this study was to evaluate 1-month simvastatin treatment effect on endothelial function in hypercholesterolemic children and adolescents. Eighteen hypercholesterolemic patients (HC group) and 18 healthy controls, aged 6–18 years, were studied with medical history, physical examination, full lipid profile,
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Collection: National databases / Brazil Database: Sec. Est. Saúde SP / SESSP-IDPCPROD Main subject: Cholesterol / Endothelium / Hypercholesterolemia Language: English Journal: Pediatr Cardiol Year: 2007 Document type: Article Institution/Affiliation country: Instituto Dante Pazzanese de Cardiologia/BR
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Collection: National databases / Brazil Database: Sec. Est. Saúde SP / SESSP-IDPCPROD Main subject: Cholesterol / Endothelium / Hypercholesterolemia Language: English Journal: Pediatr Cardiol Year: 2007 Document type: Article Institution/Affiliation country: Instituto Dante Pazzanese de Cardiologia/BR