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To breastfeed or not to breastfeed? Lack of evidence on the presence of SARS-CoV-2 in breastmilk of pregnant women with COVID-19 / Lactancia materna en mujeres con COVID-19: falta de evidencia sobre la presencia de SARS-CoV-2 en la leche materna / Aleitamento materno em mulheres com COVID-19: falta de evidência da presença da SARS-CoV-2 no leite materno
Martins-Filho, Paulo Ricardo; Santo, Victor Santana; Santos Junior, Hudson P.
Affiliation
  • Martins-Filho, Paulo Ricardo; Federal University of Sergipe. São Cristóvão. BR
  • Santo, Victor Santana; Universidade Federal de Alagoas. Arapiraca. BR
  • Santos Junior, Hudson P; University of North Carolina at Chapel Hill. Chapel Hil. US
Article in English | LILACS | ID: biblio-1095292
Responsible library: BR1.1
ABSTRACT
A rapid systematic review was carried out to evaluate the current evidence related to the presence of SARS-CoV-2 in breast milk from pregnant women with COVID-19. Eight studies analyzing the presence of SARS-CoV-2 RNA in the breast milk of 24 pregnant women with COVID-19 during the third trimester of pregnancy were found. All patients had fever and/or symptoms of acute respiratory illness and chest computed tomography images indicative of COVID-19 pneumonia. Most pregnant women had cesarean delivery (91.7%) and two neonates had low birthweight (< 2 500 g). Biological samples collected immediately after birth from upper respiratory tract (throat or nasopharyngeal) of neonates and placental tissues showed negative results for the presence SARS-CoV-2 by RT-PCR test. No breast milk samples were positive for SARS-CoV-2 and, to date, there is no evidence on the presence of SARS-CoV-2 in breast milk of pregnant women with COVID-19. However, data are still limited and breastfeeding of women with COVID-19 remains a controversial issue. There are no restrictions on the use of milk from a human breast milk bank.(AU)
RESUMO
Se llevó a cabo una revisión sistemática rápida para evaluar la evidencia disponible sobre la presencia de SARS-CoV-2 en la leche materna de mujeres embarazadas afectadas con COVID-19. Se encontraron ocho estudios que analizaron la presencia de ARN de SARS-CoV-2 en la leche materna de 24 mujeres embarazadas con COVID-19 durante el tercer trimestre del embarazo. Todas las pacientes tenían fiebre o síntomas de enfermedad respiratoria aguda e imágenes de tomografía computarizada de tórax indicativas de neumonía por COVID-19. La mayoría de las mujeres embarazadas (91,7%) tuvieron un parto por cesárea y dos neonatos presentaron bajo peso al nacer (< 2 500 g). Las muestras biológicas recogidas inmediatamente después del parto de las vías respiratorias superiores (faringe o nasofaringe) de los neonatos y los tejidos placentarios mostraron resultados negativos para SARS-CoV-2 mediante RT-PCR. Ninguna muestra de leche materna fue positiva para SARS-CoV-2 y, hasta la fecha, no hay evidencia de la presencia de SARS-CoV-2 en la leche materna de las mujeres embarazadas con COVID-19. Sin embargo, los datos disponibles todavía son limitados y la lactancia materna en las mujeres con COVID-19 sigue siendo un tema controvertido. No hay restricciones para el uso de leche materna de banco.(AU)
Subject(s)


Full text: Available Collection: International databases Database: LILACS Main subject: Breast Feeding / Coronavirus Infections / Betacoronavirus / Milk, Human Type of study: Systematic review Limits: Humans Language: English Journal: Rev. panam. salud pública Journal subject: Public Health Year: 2020 Document type: Article Affiliation country: Brazil / United States Institution/Affiliation country: Federal University of Sergipe/BR / Universidade Federal de Alagoas/BR / University of North Carolina at Chapel Hill/US

Full text: Available Collection: International databases Database: LILACS Main subject: Breast Feeding / Coronavirus Infections / Betacoronavirus / Milk, Human Type of study: Systematic review Limits: Humans Language: English Journal: Rev. panam. salud pública Journal subject: Public Health Year: 2020 Document type: Article Affiliation country: Brazil / United States Institution/Affiliation country: Federal University of Sergipe/BR / Universidade Federal de Alagoas/BR / University of North Carolina at Chapel Hill/US
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