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"Helicobacter pylori, hoy": una historia de 30 años / "Helicobacter pylori, today": a 30 year history
Sáenz F, Roque.
Affiliation
  • Sáenz F, Roque; Clínica Alemana de Santiago. CL
Rev. Méd. Clín. Condes ; 26(5): 572-578, sept. 2015. ilus
Article in Spanish | LILACS | ID: biblio-1128549
Responsible library: CL1.1
RESUMEN
En 1983, hace 30 años, Warren JR y Marshall BJ publican el artículo en Lancet1, que revolucionó el entendimiento de varias patologías gástricas, al encontrar un bacilo curvo no identificado en el epitelio gástrico, en gastritis crónica activa, de forma casi fortuita, al bacilo llamado subsecuentemente, Campylobacter pylori y con la nomenclatura de hoy, Helicobacter pylori. Fue considerado por la OMS carcinogenético gástrico el año 2001 (Figura 1). En el 2005, fueron galardonados con el Premio Nobel de Medicina, por su contribución (Figura 2). Es el tópico que más publicaciones científicas ha generado en la literatura. En la presente revisión, nos ocuparemos de un enfoque eminentemente práctico, sobre hechos de relevancia clínica de su presencia, de su diagnóstico, de la terapéutica y sus variables actuales y de los diferentes escenarios, en los cuales nos desenvolvemos. Se hace mención de un excelente documento generado en un Consenso actualizado en Latinoamérica2.
ABSTRACT
In 1983, 30 years ago, Warren JR & Marshall BJ, published in Lancet, their leading revolutionary article1, modifying the understanding of several gastric pathologies, thanks to the discovery of an unidentified curved bacilli in the gastric epithelium, in chronic active gastritis, almost unvoluntariously, nominated sequentially Campylobacter pylori and according to the today's nomenclature Helicobacter pylori. It has been considered gastric carcinogen by WHO in 2001 (Figure 1). In 2005, they were awarded with the Nobel Prize of Medicine for their contribution (Figure 2). It is the topic generating the highest number of scientific publications, in the literature. In this publication, we deal with a practical focus on clinical relevant aspects, related with its presence, its diagnosis, the therapeutic approach and its variables, and tackling the different clinical scenarios. A recently published practical Latin American consensus, has been preferently considered2.
Subject(s)


Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases Database: LILACS Main subject: Helicobacter Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: Spanish Journal: Rev. Méd. Clín. Condes Journal subject: Medicine Year: 2015 Document type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Alemana de Santiago/CL

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases Database: LILACS Main subject: Helicobacter Infections Type of study: Diagnostic study / Prognostic study Limits: Humans Language: Spanish Journal: Rev. Méd. Clín. Condes Journal subject: Medicine Year: 2015 Document type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Alemana de Santiago/CL
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