Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
Rev. Soc. Bras. Med. Trop
; 53: e20190526, 2020. tab, graf
Article
in English
| Sec. Est. Saúde SP, Coleciona SUS, LILACS
| ID: biblio-1136834
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates.METHODS:
Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using polymerase chain reaction and plasmid DNA sequencing.RESULTS:
The bla KPC-2 gene was located between ISKpn6 and a resolvase tnpR in the non-Tn4401 element (NTEKPC-IId). It was detected on a plasmid belonging to the IncQ1 group. CONCLUSIONS To our knowledge, this is the first report of the presence of the bla KPC-2 gene in the NTEKPC-IId element carried by plasmid IncQ1 from infections in Brazil.
Full text:
Available
Collection:
National databases
/
Brazil
Health context:
Neglected Diseases
Health problem:
Neglected Diseases
/
Zoonoses
Database:
LILACS
/
Sec. Est. Saúde SP
/
Coleciona SUS
Main subject:
Beta-Lactamases
/
Klebsiella Infections
/
Klebsiella pneumoniae
/
Anti-Bacterial Agents
Type of study:
Diagnostic study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2020
Document type:
Article
Institution/Affiliation country:
Centro Universitário Tabosa de Almeida/BR
/
Instituto Aggeu Magalhães/BR
/
Universidade Federal de Pernambuco/BR