Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region
Rev. Soc. Bras. Med. Trop
; 54: e20200087, 2021. tab, graf
Article
in English
| Sec. Est. Saúde SP, Coleciona SUS, LILACS
| ID: biblio-1136920
Responsible library:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of blaOXA-23 in a regional hospital located in Brazilian Amazon Region.METHODS:
The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE).RESULTS:
Only 10 (55.6%) isolates harbored the gene bla OXA-23. PFGE analysis revealed that these isolates belong to a single clone.CONCLUSIONS:
This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.
Full text:
Available
Collection:
National databases
/
Brazil
Database:
LILACS
/
Sec. Est. Saúde SP
/
Coleciona SUS
Main subject:
Acinetobacter Infections
/
Acinetobacter baumannii
Type of study:
Screening study
Limits:
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2021
Document type:
Article
Institution/Affiliation country:
Hospital Regional Público do Araguaia/BR
/
Pontifícia Universidade Católica de Goiás/BR
/
Universidade Federal de São Paulo/BR