Detection and characterization of a coxsackievirus B2 strain associated with acute meningoencephalitis, Brazil, 2018
Rev. Soc. Bras. Med. Trop
; 54: e20190499, 2021. graf
Article
in English
| Sec. Est. Saúde SP, Coleciona SUS, LILACS
| ID: biblio-1136928
Responsible library:
BR1.1
ABSTRACT
Abstract Although different etiological agents can cause acute meningoencephalitis, this syndrome is usually associated with viruses. Among these, enteroviruses play a significant role. Here, we describe a fatal case of meningoencephalitis in a previously healthy teenager. Real-time RT-PCR and cell culture assays were performed with serum and cerebrospinal fluid (CSF) from a clinically diagnosed meningoencephalitis case that occurred in Rio de Janeiro State, Brazil. Coxsackievirus B2 (CVB2) was identified. Phylogenetic analysis revealed that the identified CVB2 was genetically related to strains known to cause neurological diseases. This case highlights the importance of continuous laboratory surveillance of central nervous system infections.
Full text:
Available
Collection:
National databases
/
Brazil
Database:
LILACS
/
Sec. Est. Saúde SP
/
Coleciona SUS
Main subject:
Meningoencephalitis
Type of study:
Diagnostic study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Humans
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Year:
2021
Document type:
Article
Institution/Affiliation country:
Fundação Oswaldo Cruz/BR