Prevalence of red blood cell alloimmunization in multiply transfused patients
Clin. biomed. res
; 40(2): 91-95, 2020.
Article
in English
| LILACS
| ID: biblio-1148106
Responsible library:
BR18.1
ABSTRACT
Introduction:
To analyze the prevalence of alloantibodies in multiply transfused patients.Methods:
This study was a retrospective, exploratory and descriptive study with a quantitative approach. The study sample comprised 185 patients transfused at a referral service in the city of Passo Fundo, Rio Grande do Sul, from January 2016 to February 2018.Results:
Overall, the antibodies identified were as follows anti-E in 47 patients (18%), anti-D and anti-K in 28 patients each (11%), anti-C in 21 patients (8.1%), and inconclusive antibody results in 23 patients (8.9%). Females were a majority (55.7%), mean age was 48.8 years and mean quantity of blood transfused was 7.2 bags. Cardiovascular disorders were the most common comorbidities, in 39 patients (21.2%), followed by oncological disorders, in 38 patients (18.4%).Conclusion:
Alloimmunization is an important and frequent clinical condition that increases the risk of hemolytic reactions and is associated with significant patient morbidity and mortality. (AU)
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.3: End transmission of communicable diseases
Database:
LILACS
Main subject:
Transplant Recipients
/
Antibodies
Type of study:
Prevalence study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. biomed. res
Journal subject:
Medicine
Year:
2020
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hospital São Vicente de Paulo/BR
/
Universidade de Passo Fundo/BR