Efficacy of endometrial cancer follow-up protocols: time to change?
Rev. bras. ginecol. obstet
; 43(1): 41-45, Jan. 2021. tab
Article
in English
| LILACS
| ID: biblio-1156074
Responsible library:
BR1.1
ABSTRACT
Abstract Objective The aim of the present study was to analyze relapse rates and patterns in patients with endometrial cancer with the aim of evaluating the effectiveness of current follow-up procedures in terms of patient survival, as well as the convenience of modifying the surveillance strategy. Methods Retrospective descriptive study including all patients diagnosed with endometrial cancer relapse at the Department of Gynecology and Obstetrics of the Complejo Hospitalario Insular-Materno Infantil de Canarias, between 2005 and 2014. Results Recurrence was observed in 81 patients (10.04% of the sample); 66.7% of them suffered relapse within 2 years and 80.2% within 3 years after the termination of the primary treatment; 41.9% showed distant metastases while the rest corresponded to local-regional (40.7%) or ganglionar (17.4%) relapse; 42% of these were symptomatic; 14 patients showed more than 1 site of relapse. Relapse was detected mainly through symptoms and physical examination findings (54.3%), followed by elevated serummarker levels (29.6%), computed tomography (CT) images (9.9%) and abnormal vaginal cytology findings (6.2%). No differences in global survival were found between patients with symptomatic or asymptomatic relapse. Conclusion Taking into account that the recurrence rate of endometrial cancer is low, that relapse occurs mainly within the first 3 years post-treatment and that symptom evaluation and physical examination are the most effective follow-up methods, we postulate that a modification of the current model of hospital follow-up should be considered.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases
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SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5
Health problem:
Target 3.1: Reduce maternal mortality
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Target 3.2: Reduce avoidable death in newborns and children under 5
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Endocrine System Diseases
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Noncommunicable Diseases
Database:
LILACS
Main subject:
Clinical Protocols
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Endometrial Neoplasms
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Carcinoma, Endometrioid
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Neoplasm Recurrence, Local
Type of study:
Practice guideline
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Observational study
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Prognostic study
Limits:
Female
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Humans
Country/Region as subject:
Europa
Language:
English
Journal:
Rev. bras. ginecol. obstet
Journal subject:
Gynecology
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Obstetrics
Year:
2021
Document type:
Article
Affiliation country:
India
/
Spain
Institution/Affiliation country:
Complejo Hospitalario Universitario Insular Materno-Infantil/ES
/
Hospital Dr. Negrin/ES