Falsely elevated serum estradiol due to heterophile antibody interference: a case report
Arch. endocrinol. metab. (Online)
; 65(2): 237-241, Mar.-Apr. 2021. tab
Article
in English
| LILACS
| ID: biblio-1248806
Responsible library:
BR1.1
ABSTRACT
SUMMARY Falsely elevated estradiol is rare, may result from heterophile antibody interference, and can result in unnecessary investigation and intervention. We present the case of a 56-year-old female with falsely elevated estradiol levels inconsistent with her overall clinical picture, which ultimately led to an unnecessary surgical procedure. With the use of alternative analytical platforms and a heterophile antibody blocking agent, we determined the false elevation was due to heterophile antibody interference. Clinicians must suspect and investigate for laboratory error when the clinical picture contradicts laboratory results.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Antibodies, Heterophile
/
Estradiol
Limits:
Female
/
Humans
Language:
English
Journal:
Arch. endocrinol. metab. (Online)
Journal subject:
Endocrinology
/
Metabolism
Year:
2021
Document type:
Article
Affiliation country:
Canada
Institution/Affiliation country:
University of British Columbia/CA