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Coma irreversível em paciente portadora de esquizofrenia paranóide: encefalopatia de Wernicke após síndrome de realimentação: um relato de caso / Irreversible coma in a patient with paranoid schizophrenia: Wernicke encephalopathy after refeeding syndrome: a case report
Antonio, Ana Carolina Peçanha; Cigolini, Maicon; Secchi, Thais Leite; Mello, Juliana Mariano da Rocha Bandeira.
Affiliation
  • Antonio, Ana Carolina Peçanha; Hospital de Clínicas de Porto Alegre. Comissão de Suporte Nacional. Porto Alegre. BR
  • Cigolini, Maicon; Hospital de Clínicas de Porto Alegre. Porto Alegre. BR
  • Secchi, Thais Leite; Hospital de Clínicas de Porto Alegre. Serviço de Neurologia. Porto Alegre. BR
  • Mello, Juliana Mariano da Rocha Bandeira; Hospital de Clínicas de Porto Alegre. Porto Alegre. BR
Clin. biomed. res ; 40(4): 242-246, 2020. tab, ilus
Article in Portuguese | LILACS | ID: biblio-1252765
Responsible library: BR18.1
RESUMO
Encefalopatia de Wernicke (EW) e síndrome de realimentação (SR) são duas condições frequentemente coexistentes, subdiagnosticadas e que podem implicar prognóstico reservado após sua instalação. Sua identificação precoce representa um desafio para os intensivistas, haja vista a falta de sensibilidade e especificidade das manifestações clínicas. Apresenta-se um relato de caso de uma paciente portadora de esquizofrenia paranoide, sem histórico de abuso de álcool, que desenvolveu quadro de coma irreversível após greve de fome, sendo feito diagnóstico tardio de EW associada a SR. Descreve-se a evolução clínica e neuropsiquiátrica com o intuito de enfatizar a necessidade crucial de alta suspeição diagnóstica, com reposição vitamínica imediata, vigilância de distúrbios eletrolíticos e progressão parcimoniosa do aporte nutricional. (AU)
ABSTRACT
Wernicke encephalopathy (WE) and refeeding syndrome (RFS) are two often coexisting, underdiagnosed conditions that may involve a poor prognosis after their onset. Early identification represents a challenge for intensivists, given the lack of sensitivity and specificity of clinical manifestations. We report a case of a patient with paranoid schizophrenia, without a history of alcohol abuse, who developed irreversible coma after a hunger strike, with a late diagnosis of WE associated with RFS. The clinical and neuropsychiatric outcomes are described herein in order to emphasize the crucial need for a high diagnostic suspicion, with immediate vitamin replacement, monitoring of electrolyte disorders, and gradual progression of nutritional support. (AU)
Subject(s)


Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Target 3.5: Prevention and treatment of consumption of psychoactive substances / Alcohol Database: LILACS Main subject: Wernicke Encephalopathy / Coma / Refeeding Syndrome Type of study: Diagnostic study / Prognostic study Limits: Female / Humans Language: Portuguese Journal: Clin. biomed. res Journal subject: Medicine Year: 2020 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital de Clínicas de Porto Alegre/BR

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Target 3.5: Prevention and treatment of consumption of psychoactive substances / Alcohol Database: LILACS Main subject: Wernicke Encephalopathy / Coma / Refeeding Syndrome Type of study: Diagnostic study / Prognostic study Limits: Female / Humans Language: Portuguese Journal: Clin. biomed. res Journal subject: Medicine Year: 2020 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Hospital de Clínicas de Porto Alegre/BR
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