Cotrimoxazole (septrin) prophylaxis in the management of vesico-vaginal fistulae in Ilorin; Nigeria

ABSTRACT

In a 5-year period (1986-1990) 83 Nigerian women with mid vaginal vesico-vaginal fistulae (VVF) were treated in the University of Ilorin Teaching Hospital; Ilorin; Nigeria. None of the patients had previous antibiotic therapy before this study. 30 patients received cotrimoxazole (Trimethoprim 80mg; sulphamethoxazole 400mg) two tablets twice daily for 7 days before surgery without sterile urine preparation; 27 similar patients had the same treatment only after surgery; while 26 other patients who had sterile urine preparation before surgery were not given any antibiotics after surgery