Screening tool for restrictive and obstructive ventilatory abnormalities in a population-based survey
Rev. invest. clín
; 72(6): 386-393, Nov.-Dec. 2020. tab, graf
Article
in English
| LILACS
| ID: biblio-1289734
Responsible library:
BR1.1
ABSTRACT
Abstract Background:
A 6 s spirometry with an inexpensive pocket spirometer efficiently selects individuals for a diagnostic-quality spirometry for airflow limitation, but could also be useful to identify individuals with a restrictive pattern.Objectives:
We evaluated an inexpensive simplified spirometer (chronic obstructive pulmonary disease [COPD]-6) as a screening tool to identify spirometric abnormalities.Methods:
A population-based survey in Mexico City, with 742 participants performing pre- and post-BD spirometry and a three-maneuver 6 s spirometry (pre-BD) with a COPD-6. We evaluated forced expiratory volume in 1 s (FEV1), FEV6, and FEV1/FEV6 from the COPD-6, crude and expressed as the percentage of predicted (%P), to discriminate post-bronchodilator airflow obstruction (FEV1/forced vital capacity [FVC] <5th percentile) or restriction (FVC or FEV1 <5th percentile with normal FEV1/FVC) through receiver operating characteristics and their area under the curve (AUC).Results:
FEV1%P was the best predictor to identify pre- and post-BD ventilatory abnormalities (best cutoff point 87%P, AUC 92% for restrictive pattern, 89% for obstructive pattern, and 91% for any spirometric abnormality). Deriving to clinical spirometry only those with <87%P (26% of the sample) missed only 12% of spirometric abnormalities most of the latter mild.Conclusions:
An FEV1 <87%P from a pre-BD 6 s spirometry correctly identified individuals with spirometric ventilatory defects, either obstructive or restrictive.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
Health problem:
Target 3.4: Reduce premature mortality due to noncommunicable diseases
Database:
LILACS
Main subject:
Spirometry
/
Mass Screening
/
Pulmonary Disease, Chronic Obstructive
Type of study:
Diagnostic study
/
Prognostic study
/
Screening study
Limits:
Adult
/
Humans
Country/Region as subject:
Mexico
Language:
English
Journal:
Rev. invest. clín
Journal subject:
Medicine
Year:
2020
Document type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas/MX