Dengue Virus Serotype 2 Established in Northern Mozambique (20152016)
The American Journal of Tropical Medicine and Hygiene
; 97(5): 1418-1422, 20170000. ilus, graf
Article
in English
| RSDM
| ID: biblio-1355220
Responsible library:
MZ10
ABSTRACT
After the report of an outbreak of dengue virus serotype 2 in 2014 in Nampula and Pemba cities, northernMozambique, a surveillance system was established by the National Institute of Health. A study was performed during20152016 to monitor the trend of the outbreak and confirm the circulating serotype of dengue virus (DENV). After theinclusion of consenting patients who met the case definition, samples from 192 patients were tested for the presence ofnonstructural protein1antigen,and60/192(31%)sampleswerepositive.FurtheranalysisincludedDENVIgMantibodies,with 39 (20%) IgM positive cases. Reverse transcriptase (RT) PCR was performed for identification of the prevailing DENVserotype; 21/23 tested samples were DENV-2 positive, with DENV-2 present in both affected cities. When sequencingDENV, phenotype Cosmopolitan was identified. The surveillance indicates ongoing spread of DENV-2 in northernMozambique 2 years after thefirst report of the outbreak.
Full text:
Available
Collection:
National databases
/
MZ
Health context:
Neglected Diseases
Health problem:
Dengue
/
Neglected Diseases
Database:
RSDM
Main subject:
Dengue Virus
Limits:
Humans
Language:
English
Journal:
The American Journal of Tropical Medicine and Hygiene
Year:
2017
Document type:
Article
Institution/Affiliation country:
Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet/SE
/
Department ofLaboratory Medicine, Karolinska Institutet, Stockholm, Sweden/SE
/
National Institute of Health, Ministry of Health/MZ
/
Oswaldo Cruz Institute, Flavivirus Reference Laboratory/BR