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Hipomelanosis macular progresiva: respuesta al tratamiento con minociclina / Progressive macular hypomelanosis: response to treatment with minocycline
Giusti, Fátima; Consigli, Carlos; Consigli, Javier; Cippitelli, Lorena; Mazzotta, Marco.
Affiliation
  • Giusti, Fátima; Universidad Nacional de Córdoba. Córdoba. AR
  • Consigli, Carlos; Universidad Nacional de Córdoba. Córdoba. AR
  • Consigli, Javier; Universidad Nacional de Córdoba. Córdoba. AR
  • Cippitelli, Lorena; Universidad Nacional de Córdoba. Córdoba. AR
  • Mazzotta, Marco; Universidad Nacional de Córdoba. Córdoba. AR
Dermatol. argent ; 27(1): 31-33, ene.-mar. 2021. il
Article in Es | LILACS, BINACIS | ID: biblio-1361658
Responsible library: AR144.1
Localization: AR144.1; 616.5/25
RESUMEN
La hipomelanosis macular progresiva (HMP) es una dermatosis caracterizada por máculas hipopigmentadas, que se observa con mayor frecuencia en las mujeres y en los fototipos III y IV. Se ha asociado a Cutibacterium acnes (C. acnes) de tipo III como factor etiológico. Se presenta el caso de una paciente de 30 años, con máculas hipopigmentadas redondeadas en el tronco y la raíz de los miembros inferiores, de 10 años de evolución. El estudio histológico informó disminución del número de melanocitos y de pigmento melánico en la capa basal e infiltrado inflamatorio mononuclear perivascular superficial. Se indicó minociclina 100 mg/día por vía oral durante 8 meses, tras lo cual se observó la resolución total de las lesiones.
ABSTRACT
Progressive macular hypomelanosis (PMH) is a dermatosis characterized by hypopigmented macules, most frequently found in females and in phototypes III and IV. Cutibacterium acnes (C. acnes) type III has been associated as an etiological factor. We present the case of a thirty-year-old female patient with a 10-year history of nummular hypopigmented macules located on the top of the lower limbs and on the trunk. The histological study reported a decrease in the number of melanocytes and melanotic pigment in the basal layer and the presence of superficial perivascular mononuclear inflammatory infiltrate. After an 8-month regimen of oral minocycline 100 mg/day, there was a complete resolution of the lesions.
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Full text: 1 Collection: 01-internacional Database: BINACIS / LILACS Main subject: Melanosis / Minocycline Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: Es Journal: Dermatol. argent Journal subject: DERMATOLOGIA Year: 2021 Document type: Article Affiliation country: Argentina Country of publication: Argentina

Full text: 1 Collection: 01-internacional Database: BINACIS / LILACS Main subject: Melanosis / Minocycline Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: Es Journal: Dermatol. argent Journal subject: DERMATOLOGIA Year: 2021 Document type: Article Affiliation country: Argentina Country of publication: Argentina