Effect of rape flower on benign prostatic hyperplasia in rats
Braz. J. Pharm. Sci. (Online)
; 58: e18785, 2022. graf
Article
in English
| LILACS
| ID: biblio-1364421
Responsible library:
BR40.1
Localization: BR40.1
ABSTRACT
We were carried out to investigate the efficacy of Rape (Rapeseed, Brassica napus L.) flower on BPH (benign prostatic hyperplasia) in rats. We found that the extract from Rape flower prevented hyperplasia in testosterone-induced BPH model, the relevant animal model of human BPH. Extract reduced the weight of prostate and induced significantly cell apoptosis in prostate in BPH model. In addition, the extract controlled expression of TGF-ß1 in prostate gland and promoted urinary output in dose-dependence in BPH model. Our data provide that Rape flower may be useful for treatment of BPH
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Prostatic Hyperplasia
/
Efficacy
/
Brassica napus
/
Flowers
Limits:
Animals
Language:
English
Journal:
Braz. J. Pharm. Sci. (Online)
Journal subject:
Farmacologia
/
Teraputica
/
Toxicologia
Year:
2022
Document type:
Article
Affiliation country:
North Korea
Institution/Affiliation country:
Kim Il Sung University/KP