Enfermedad relacionada con IgG4: reporte de un caso y revisión de la literatura / IgG4-related disease: a case report and literature review
Rev. méd. Maule
; 36(2): 60-68, dic. 2021.
Article
in Spanish
| LILACS
| ID: biblio-1378505
Responsible library:
CL1.1
ABSTRACT
Immunoglobulin G4 (IgG4-RD) -related disease is a regional or systemic fibroinflammatory disease of unknown etiology. It has a characteristic histopathological appearance of dense lymphoplasmacytic infiltrates with abundant IgG4 positive plasma cells, storiform fibrosis and obliterative phlebitis with the appearance of inflammatory swelling or swollen lesions. This entity frequently affects the pancreas, salivary glands, and lymph nodes, but it can compromise almost any structure in the human anatomy. This new disease entity includes a wide variety of diseases such as Mikulicz disease, autoimmune pancreatitis, Riedel's thyroiditis, interstitial nephritis, and retroperitoneal fibrosis. Glucocorticoid therapy can resolve clinical and pathologic abnormalities and impaired organ function. IgG4-RD was internationally recognized in 2011, and new evidence has accumulated on its pathogenesis, clinical characteristics, and treatment. However, much is still unknown about the behavior of IgG4 in vivo, the participation of this molecule in disease, and whether its role in IgG4-related disease is primary or secondary. The text below is based on a brief review of the most recent literature on this entity in relation to a clinical case.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Target 3.8 Achieve universal access to health
Health problem:
Delivery Arrangements
Database:
LILACS
Main subject:
Autoimmune Diseases
/
Immunoglobulin G4-Related Disease
Limits:
Aged
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Maule
Journal subject:
Medicine
Year:
2021
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Regional de Talca/CL
/
Universidad Autónoma de Chile/CL