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Aceptabilidad a usar profilaxis pre-exposición para VIH en hombres gay y otros hombres que tienen sexo con hombres: indagación en LAMIS 2018 Chile / Acceptability of pre-exposure prophylaxis for HIV prevention among gay men and other men who have sex with men: analysis of LAMIS 2018-Chile
Adrian P, Constanza; Stuardo Á, Valeria.
Affiliation
  • Adrian P, Constanza; Universidad de Chile. Escuela de Salud Pública. CL
  • Stuardo Á, Valeria; Universidad de Chile. Escuela de Salud Pública. CL
Rev. chil. infectol ; 38(5): 655-666, oct. 2021. tab
Article in Spanish | LILACS | ID: biblio-1388299
Responsible library: CL1.1
RESUMEN

INTRODUCCIÓN:

Chile enfrenta una reemergencia de la epidemia del VIH concentrada en hombres gay y otros HSH. La profilaxis pre exposición (PrEP) es una intervención biomédica que ha resultado ser efectiva en la prevención del VIH en el grupo de HSH.

OBJETIVO:

Estimar niveles de aceptabilidad del uso de PrEP en hombres gay y otros HSH participantes en estudio LAMIS 2018 - Chile, identificando características y factores asociados a la aceptabilidad del uso de PrEP. MATERIAL Y

MÉTODOS:

Estudio basado en datos de LAMIS-2018 Chile, encuesta transversal por internet dirigida a hombres gay, bisexual, trans y otros HSH. La submuestra de este estudio consiste en 3.976 participantes que se auto-reportaron ser VIH negativos o desconocer su estado serológico, quienes respondieron preguntas sociodemográficas, de comportamiento, sobre su aceptabilidad a usar PrEP y otros aspectos relacionados. Se realizó análisis bivariados y regresión logística multivariable para identificar los factores asociados a la aceptabilidad a usar PrEP. RESULTADOS Y

DISCUSIÓN:

Se identificó que 55,7% de la muestra reportó una alta aceptabilidad a usar la PrEP. La regresión logística multivariable mostró que tener relaciones sexuales sin condón (ORa = 1,67, IC 95% 1,42-1,97) y haber intentado usar PrEP (ORa = 1,99, IC 95% 1,41-1, 62) se asociaron positivamente a la aceptabilidad a usar PrEP mientras que tener una relación con pareja estable, se asoció negativamente. Se identificó una aceptabilidad a usar la PrEP relativamente alta en los participantes. No obstante, se hace necesario considerar intervenciones relacionada a aumentar el conocimiento y promover la demanda de la PrEP. Además, el presente estudio muestra la necesidad de considerar la participación de las organizaciones de la sociedad civil en su implementación, fenómenos emergentes y la pertinencia territorial.
ABSTRACT

BACKGROUND:

Chile is facing a re-emergence of the HIV epidemic, concentrated among men who have sex with men (MSM). Pre-exposure prophylaxis (PrEP) is a biomedical intervention that effectively prevents HIV transmission among MSM.

AIM:

The study was designed to estimate acceptability of PrEP and identify factors associated with PrEP-related attitudes and behaviors among MSM using LAMIS 2018 - Chile study data.

Methods:

Data were taken from the LAMIS 2018 - Chile study, a cross-sectional study of gay, bisexual, transgender, and other MSM. Our subsample included 3976 participants with self-reported HIV-negative or unknown status who responded to sociodemographic questions and items related to PrEP. Bivariate analysis and multivariate logistic regression analysis were performed to identify factors associated with acceptability of PrEP. RESULTS AND

DISCUSSION:

A total of 55.7% of the sample reported high PrEP acceptability. Logistic regression indicated that engaging in sex without a condom (ORa = 1.67, IC 95% 1.42-1.97) and having previously used PrEP (ORa = 1.99, IC 95% 1.41-1.62) were associated with high acceptability to use PrEP, while having a stable partner was associated with low acceptability. The estimate of PrEP acceptability was relatively high among participants. However, interventions to increase awareness and promote demand for PrEP may be beneficial. Furthermore, this study demonstrates the need for non-governmental organizations to participate in such strategies and for measures that address regionally-relevant emerging phenomena.
Subject(s)


Full text: Available Collection: International databases Health context: SDG3 - Target 3.9 Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil / Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Occupational Exposures / Goal 9: Noncommunicable diseases and mental health / Target 3.3: End transmission of communicable diseases Database: LILACS Main subject: HIV Infections / Anti-HIV Agents / Pre-Exposure Prophylaxis / Sexual and Gender Minorities Type of study: Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. chil. infectol Journal subject: Communicable Diseases Year: 2021 Document type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL

Full text: Available Collection: International databases Health context: SDG3 - Target 3.9 Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil / Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being Health problem: Occupational Exposures / Goal 9: Noncommunicable diseases and mental health / Target 3.3: End transmission of communicable diseases Database: LILACS Main subject: HIV Infections / Anti-HIV Agents / Pre-Exposure Prophylaxis / Sexual and Gender Minorities Type of study: Observational study / Prevalence study / Prognostic study / Qualitative research / Risk factors Limits: Female / Humans / Male Country/Region as subject: South America / Chile Language: Spanish Journal: Rev. chil. infectol Journal subject: Communicable Diseases Year: 2021 Document type: Article Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL
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