Mortalidad en pacientes hospitalizados por COVID-19. Estudio prospectivo en el norte del Perú, 2020 / Mortality in patients hospitalized with COVID-19 in northern Peru
Rev. méd. Chile
; 149(10): 1459-1466, oct. 2021. tab
Article
in Spanish
| LILACS
| ID: biblio-1389373
Responsible library:
CL126.2
ABSTRACT
BACKGROUND:
Peru has one of the highest mortality rates due to COVID-19 in the world.AIM:
To describe the clinical features, evolution and explore factors associated with mortality in patients with moderate to severe Covid-19. MATERIAL ANDMETHODS:
Prospective analytical study. The clinical, laboratory, imaging, and mortality data of patients admitted at a COVID service of the Santa Rosa de Piura Hospital were recorded from April to June 2020.RESULTS:
Data from 391 patients with a median age of 60 years (70% women) was gathered. The time lapse between the onset of the disease and hospitalization was seven days. The most common alteration in the blood count was Neutrophilia in 78% of patients. The median PaO2/FiO2 ratio was 77. The distribution of tomographic patterns was Ground glass in 91% of patients, interstitial involvement in 57%, consolidation in 43%. Sixteen percent of patients had at least one complication, the most common was an increase in transaminases in 2%. Four percent were admitted to the intensive care unit and 53% died (94% during hospitalization and 5.8% during ICU stay). In the bivariate analysis, an association was found between a higher mortality and older age (p = 0.01), having fewer days of illness (p = 0.03), fewer days of hospital stay (p < 0.01), having at least one comorbidity (p = 0.02), lymphopenia (p = 0.02), neutrophilia (P = 0.03) and lower PaO2/ FiO2 ratio (p < 0.01).CONCLUSIONS:
Fifty percent of these patients died. Age, rapid progression, having comorbidities and other laboratory alterations were associated with mortality.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
COVID-19
Type of study:
Observational study
/
Risk factors
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Peru
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2021
Document type:
Article
Affiliation country:
Peru
Institution/Affiliation country:
Hospital Santa Rosa Piura/PE
/
Sanidad del Grupo 7-FAP/PE
/
Universidad Norbert Wiener/PE
/
Universidad San Ignacio de Loyola/PE