Triclosan antimicrobial activity against dental-caries-related bacteria
Braz. j. oral sci
; 22: e238076, Jan.-Dec. 2023. ilus
Article
in English
| LILACS, BBO - Dentistry
| ID: biblio-1393427
Responsible library:
BR218.1
ABSTRACT
Triclosan (TCS) is a chlorinated diphenyl ether and a possible active agent against microorganisms. Due to its probability of reducing dental plaque accumulation, TCS can be added as a substance for oral hygiene. Aim:
To evaluate the efficacy and antimicrobial capacity of TCS against Pseudomonas aeruginosa and Streptococcus mutans.Methods:
This work evaluates the percentage of bacteria inhibition of P. aeruginosa (ATCC 27853) and S. mutans (ATCC 25175). TCS concentrations between 2 and 128 µg.mL-1 were tested.Results:
An inhibitory potential of TCS was found against S. mutans. No percentage of inhibition was detected against P. aeruginosa (technical and biological triplicate).Conclusion:
TCS, an antimicrobial agent used in dentifrices, can reduce S. mutans levels therefore these dentifrices should be indicated for patients with a high risk of caries. However, further study is needed, including antimicrobial analyses against other microbial conditionsSubject(s)
Full text:
Available
Collection:
International databases
Database:
BBO - Dentistry
/
LILACS
Main subject:
Pseudomonas aeruginosa
/
Streptococcus mutans
/
Triclosan
/
Dental Caries
/
Oral and Dental Hygiene Products
/
Anti-Infective Agents, Local
/
Mouth Diseases
Language:
English
Journal:
Braz. j. oral sci
Journal subject:
Dentistry
Year:
2023
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Catholic University of Brasilia/BR
/
Catholic University of Brasília/BR
/
University of Brasília/BR