Human enteroviral infection in fibromyalgia: a case-control blinded study
Rev. Assoc. Med. Bras. (1992, Impr.)
; 68(7): 945-947, July 2022. tab
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1394577
Responsible library:
BR1.1
ABSTRACT
SUMMARY OBJECTIVE:
This study aimed to test the hypothesis that fibromyalgia is associated with a human enteroviral infection.METHODS:
Venous peripheral blood samples from 27 patients fulfilling the American College of Rheumatology revised diagnostic criteria for fibromyalgia and from 26 age- and sex-matched controls, who underwent immunofluorescence assays for coxsackievirus A7 IgG, coxsackievirus B1 IgG, coxsackievirus A7 IgA, coxsackievirus B1 IgA, echovirus IgG, and echovirus IgA. These immunological tests were performed blind to group status.RESULTS:
There were no significant differences between the patient and control groups in respect of positive results for coxsackievirus A7 IgG (p=0.467), coxsackievirus B1 IgG (p=0.491), coxsackievirus A7 IgA (p=0.586), coxsackievirus B1 IgA (p=0.467), echovirus IgG (p=0.236), and echovirus IgA (p=1).CONCLUSIONS:
The results of this systematic study do not support the hypothesis that fibromyalgia is associated with infection by a human enterovirus.
Full text:
Available
Collection:
International databases
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 10: Communicable diseases
Database:
LILACS
Type of study:
Observational study
Language:
English
Journal:
Rev. Assoc. Med. Bras. (1992, Impr.)
Journal subject:
EducaÆo em Sa£de
/
GestÆo do Conhecimento para a Pesquisa em Sa£de
/
Medicine
Year:
2022
Document type:
Article
Affiliation country:
Germany
/
United kingdom
Institution/Affiliation country:
ArminLabs GmbH/DE
/
University of Southampton/GB
/
University of Winchester/GB