Leucemia mieloide crónica atípica BCR-ABL1 negativa: reporte de 2 casos / BCR-ABL1 negative chronic myeloid leukemia: report of two cases
Rev. méd. Chile
; 150(3): 397-401, mar. 2022. ilus, tab
Article
in Spanish
| LILACS
| ID: biblio-1409816
Responsible library:
CL126.2
ABSTRACT
BCR-ABL1 negative atypical chronic myeloid leukemia (aCML) is a rare type of myeloproliferative / myelodysplastic syndrome characterized by leukocytosis and proliferation of dysplastic neutrophilic precursors in the absence of positivity for the BCR-ABL1 fusion gene. We report a 66-year-old woman and a 57-year-old man with aCML, who initially presented with general malaise and weight loss, associated with anemia, thrombocytopenia, and leukocytosis with left shift and dysplasia in the neutrophil series. Both evolved unfavorably after admission and died a few days later due to multiple organ failure.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Thrombocytopenia
/
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
/
Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2022
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Concepción/CL