A review of serological tests available in Brazil for intestinal schistosomiasis diagnosis
Mem. Inst. Oswaldo Cruz
; 118: e230236, 2023. tab
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1422152
Responsible library:
BR1.1
ABSTRACT
The World Health Organization (WHO) roadmap and recommendations for elimination of schistosomiasis were recently updated. With significant reductions in the prevalence and intensity of schistosomiasis infections worldwide, there is a need for more sensitive diagnostic methods. There are a few remaining transmission hotspots in Brazil, although low endemicity settings comprise most of the endemic localities. For the latter, serology may represent a tool for population screening which could help eliminate transmission of schistosomiasis. Here, we review serology tests currently available in Brazil from both public health and private laboratories immunofluorescent antibody tests (IFATs) on adult worm sections and enzyme-linked immunosorbent assays (ELISAs) with soluble egg and adult worm antigens. Both in-house and commercially available tests have received less than adequate performance evaluations. Our review of immediate basic and operational research goals may help identify local adjustments that can be made to improve control interventions aimed at elimination of schistosomiasis as a public health problem.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
Health problem:
Target 3.8 Achieve universal access to health
/
Target 3.3: End transmission of communicable diseases
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Neglected Diseases
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Schistosomiasis
/
Zoonoses
Database:
LILACS
Type of study:
Diagnostic study
/
Practice guideline
/
Risk factors
Country/Region as subject:
South America
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Brazil
Language:
English
Journal:
Mem. Inst. Oswaldo Cruz
Journal subject:
Tropical Medicine
/
Parasitology
Year:
2023
Document type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Fundação Oswaldo Cruz-Fiocruz/BR
/
Universidade Federal do Espírito Santo/BR