Effect of Xylitol Varnishes on the Inhibition of Demineralization in Vitro
Pesqui. bras. odontopediatria clín. integr
; 22: e210205, 2022. tab, graf
Article
in English
| LILACS, BBO - Dentistry
| ID: biblio-1422251
Responsible library:
BR1264.1
ABSTRACT
Abstract Objective:
To evaluate the efficacy of xylitol varnishes in the inhibition of enamel demineralization in vitro. Material andMethods:
Bovine enamel blocks (n=120) were randomly allocated to four groups (n = 30), and the surface hardness (SH) was measured at baseline. The blocks were treated with the following varnishes 20% xylitol, 20% xylitol plus F (5% NaF), Duraphat™ (5% NaF, positive control), and placebo (no-F/xylitol, negative control). The varnishes were applied and removed after 6 h of immersion in artificial saliva. The blocks were subjected to pH cycles (demineralization and remineralization for 2 and 22h/day, respectively, for 8 days). Surface and cross-sectional hardnesses were measured to calculate the percentage of SH loss (%SHL) and the integrated loss of the subsurface hardness (ΔKHN). Data were statistically analyzed using Kruskal-Wallis and Tukey's tests (p<0.05).Results:
%SHL was significantly decreased by 20% xylitol plus F, Duraphat™, and 20% xylitol varnishes compared to placebo. The use of 20% xylitol plus F varnish led to a significantly lower percentage of SH loss compared to the use of 20% xylitol varnish without F. However, the experimental and commercial varnishes led to significantly lower subsurface demineralization compared to placebo and did not differ from each other.Conclusion:
Xylitol varnishes, especially when combined with F, effectively prevent enamel demineralization (AU).
Full text:
Available
Collection:
International databases
Database:
BBO - Dentistry
/
LILACS
Main subject:
Xylitol
/
Tooth Demineralization
/
Dental Caries
/
Dental Enamel
Type of study:
Controlled clinical trial
Limits:
Animals
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2022
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Cruzeiro do Sul University/BR
/
Municipal University of São Caetano do Sul/BR
/
University of São Paulo/BR