Expression analysis of m6A-related genes in various tissues of Meishan pigs at different developmental stages
Rev. bras. zootec
; 52: e20210149, 2023. tab, graf
Article
in En
| VETINDEX
| ID: biblio-1436790
Responsible library:
BR68.1
Localization: BR68.1
ABSTRACT
To characterize the N6-methyladenosine (m6A)-related gene expression profiles in various tissues of Meishan pigs at different stages, m6A modification-related genes (METTL3, METTL14, METTL16, WTAP, RBM15, and FTO) were detected from newborn to physical maturity of Meishan pigs at eight important developmental stages (1, 7, 14, 21, 28, 35, 134, and 158 days old). The expression of m6A-related genes was tissue-specific. Furthermore, the level of METTL3 messenger RNA (mRNA) was higher on day 35 than in other stages in most tissues, and the expression of METTL14 increased after day 35, and FTO exhibited a peak on day 14 in muscle, intestine, lymph nodes, thymus, and kidney. This study provided a reference for an in-depth study of the expression patterns of m6A modification-related genes in Meishan pigs.
Key words
Full text:
1
Database:
VETINDEX
Main subject:
Swine
/
Genes
/
Life Cycle Stages
Limits:
Animals
Language:
En
Journal:
Rev. bras. zootec
Year:
2023
Document type:
Article