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A associação entre câncer colorretal e índice de qualidade nutricional (INQ); um estudo de caso-controle / The association between colorectal cancer and index of nutritional quality (inq); a case-control study
GHOLAMALIZADEH, Maryam; SHEKARI, Soheila; HASSANPOUR ARDEKANIZADEH, Naeemeh; VAHID, Farhad; ASLANI, Zahra; AKBARI, Mohammad Esmail; ALEMRAJABI, Mahdi; LAVASANI, Ali; HAJIPOUR, Azadeh; HOSSEINZADEH, Payam; ASBAGHI, Omid; DOAEI, Saeid.
Affiliation
  • GHOLAMALIZADEH, Maryam; Shahid Beheshti University of Medical Sciences. Cancer Research Center. Tehran. IR
  • SHEKARI, Soheila; Islamic Azad University. Science and Research Branch. Department of Nutrition. Tehran. IR
  • HASSANPOUR ARDEKANIZADEH, Naeemeh; Shiraz University of Medical Sciences. School of Nutrition and Food Sciences. Department of Clinical Nutrition. Shiraz. IR
  • VAHID, Farhad; Luxembourg Institute of Health. Nutrition and Health Research Group. Department of Precision Health. Strassen. LU
  • ASLANI, Zahra; The Ohio State University. Program in Nutrition (OSUN). Columbus. US
  • AKBARI, Mohammad Esmail; Shahid Beheshti University of Medical Sciences. Cancer Research Center. Tehran. IR
  • ALEMRAJABI, Mahdi; Iran University of Medical Sciences. School of Medicine. Clinical Research Development Center (CRDC). Tehran. IR
  • LAVASANI, Ali; Iran University of Medical Sciences. School of Medicine. Clinical Research Development Center (CRDC). Tehran. IR
  • HAJIPOUR, Azadeh; Qazvin University of Medical Sciences. School of Health. Qazvin. IR
  • HOSSEINZADEH, Payam; Iran University of Medical Sciences. Gastrointestinal and Liver Diseases Research Center (GILDRC). Tehran. IR
  • ASBAGHI, Omid; Shahid Beheshti University of Medical Sciences. Cancer Research Center. Tehran. IR
  • DOAEI, Saeid; Shahid Beheshti University of Medical Sciences. Faculty of Nutrition and Food Technology. Department of Community Nutrition. Tehran. IR
Arq. gastroenterol ; 60(2): 217-223, Apr.-June 2023. tab
Article in English | LILACS-Express | LILACS | ID: biblio-1447394
Responsible library: BR1.1
ABSTRACT
ABSTRACT

Background:

The nutritional quality of diet may influence the risk of colorectal cancer (CRC). This study compared the Index of Nutritional Quality (INQ) of various dietary components between colorectal cancer patients and healthy controls.

Methods:

A total of 480 participants were enrolled in the study (160 patients with colorectal cancer as a case group and 320 healthy control). An analysis was conducted on the general characteristics of the participants, their medical histories, anthropometric indicators, physical activity, alcohol consumption, reproductive history, smoking and food intake. A valid food frequency questionnaire was used to assess nutrient intake and INQ was calculated from daily nutrient intake.

Results:

A Significant inverse association was found between CRC and INQ for vitamins A (OR=0.01, CI 0.01-0.01), K (OR=0.04, CI 0.01-0.15), and B12 (OR=0.71, CI 0.51-0.98), B5 (OR=0.43, CI 0.00-0.01), zinc (OR=0.35, CI 0.13-0.95), and phosphorus (OR=0.17, 0.19-0.94). The association between the INQ of vitamin B12 and zinc with colorectal cancer was disappeared after age adjustment. There was a significant negative association between CRC with the INQ of vitamins A, K, B5, phosphorus, and calcium after further adjustments for gender, BMI, menopausal status, and total energy intake.

Conclusion:

CRC is significantly associated with INQ for some micronutrients. INQ can be considered as an indicator to assess clinical nutritional problems.
RESUMO
RESUMO

Contexto:

A qualidade nutricional da dieta pode influenciar o risco de câncer colorretal (CCR). Este estudo comparou o Índice de Valor Nutricional (INQ) de vários componentes dietéticos entre pacientes com CCR e controles saudáveis.

Métodos:

Um total de 480 participantes foram inscritos no estudo (160 pacientes com CCR como um grupo de casos e 320 controles saudáveis). Uma análise foi conduzida sobre as características gerais dos participantes, seus históricos médicos, indicadores antropométricos, atividade física, consumo de álcool, histórico reprodutivo, tabagismo e ingestão de alimentos. Um questionário de frequência alimentar válido foi usado para avaliar a ingestão de nutrientes e o INQ foi calculado a partir da ingestão diária de nutrientes.

Resultados:

Associação significativa entre CCR e INQ para as vitaminas A (OR=0,00, IC 0,00-0,01), K (OR=0,04, IC 0,01-0,15), B12 (OR=0,71, IC 0,51-0,98) houve uma associação negativa), B5 (OR=0,43, IC 0,00-0,01), zinco (OR=0,35, IC 0,13-0,95), fósforo (OR=0,17, IC 0,19-0,94). A associação entre o INQ da vitamina B12, zinco e CCR desapareceu após o ajuste pela idade. Houve uma associação negativa significativa entre CCR e INQ de cálcio, e outros resultados não mudaram após ajustes adicionais para idade, gênero, Índice de Massa Corporal, estado de menopausa e ingestão total de energia.

Conclusão:

CCR está significativamente associado ao INQ para alguns micronutrientes. O INQ pode ser usado como um indicador para avaliar problemas nutricionais clínicos.


Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Alcohol Database: LILACS Type of study: Observational study / Risk factors Language: English Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2023 Document type: Article / Project document Affiliation country: Iran / Luxembourg / United States Institution/Affiliation country: Iran University of Medical Sciences/IR / Islamic Azad University/IR / Luxembourg Institute of Health/LU / Qazvin University of Medical Sciences/IR / Shahid Beheshti University of Medical Sciences/IR / Shiraz University of Medical Sciences/IR / The Ohio State University/US

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Goal 9: Noncommunicable diseases and mental health / Target 3.4: Reduce premature mortality due to noncommunicable diseases / Alcohol Database: LILACS Type of study: Observational study / Risk factors Language: English Journal: Arq. gastroenterol Journal subject: Gastroenterology Year: 2023 Document type: Article / Project document Affiliation country: Iran / Luxembourg / United States Institution/Affiliation country: Iran University of Medical Sciences/IR / Islamic Azad University/IR / Luxembourg Institute of Health/LU / Qazvin University of Medical Sciences/IR / Shahid Beheshti University of Medical Sciences/IR / Shiraz University of Medical Sciences/IR / The Ohio State University/US
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