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Efecto osteoinductor del mineral trióxido agregado versus el cemento Portland tipo I sobre lesiones óseas mandibulares
Erazo Paredes, Carlos Humberto; Ruíz Ramírez, Eliberto; Barreda Torres, Oscar Alberto; Aguirre Siancas, Elías Ernesto.
Affiliation
  • Erazo Paredes, Carlos Humberto; s.af
  • Ruíz Ramírez, Eliberto; s.af
  • Barreda Torres, Oscar Alberto; s.af
  • Aguirre Siancas, Elías Ernesto; s.af
Odontol. vital ; jun. 2016.
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1506838
Responsible library: CR1.1
RESUMEN

Introducción:

Estudio experimental donde se procuró determinar el efecto osteoinductor del mineral trióxido agregado (MTA) versus el cemento Portland tipo I sobre lesiones óseas mandibulares.

Metodología:

Se emplearon 12 conejos machos de la raza New Zealand de 3 meses de edad, los cuales fueron divididos en 4 grupos iguales. Todos los conejos fueron anestesiados utilizando pentobarbital sódico. Se procedió a la incisión en la piel mandibular para exponer el hueso sobre el que se realizó 3 cavidades de 3mm cada una. En una cavidad se colocó MTA, en otra cemento Portland y en la tercena ninguna pasta. Se procedió al sacrificio de los grupos experimentales a la 1era, 2da, 3era y 4ta semana respectiva y se evaluó las muestras obtenidas de las áreas quirúrgicas mediante conteo de osteocitos y osteoblastos.

Resultados:

Tanto el MTA como el cemento Portland poseen la misma capacidad osteoinductiva en la 1era, 2da y 3era semana (p>0,05). Sin embargo, en la 4ta semana el MTA tuvo mayor capacidad osteoinductora al estimular mayor número de osteoblastos que el cemento Portland (p=0,024).

Conclusiones:

El MTA y el cemento Portland tipo I mostraron similar efecto osteoinductor durante las 3 primeras semanas de evaluación. El MTA demostró mayor efecto osteoinductor durante la cuarta semana de valoración.
ABSTRACT

Introduction:

An experimental study was carried out to determine the osteoinductive effect of Mineral Trioxide Aggregate (MTA) versus Portland Cement type I on mandibular bone lesions.

Methodology:

Twelve 3-month-old male New Zealand rabbits were divided into 4 equal groups. All rabbits were anesthetized using Pentobarbital. An incision of the mandibular skin was performed to expose the bone on which 3 cavities of 2mm each one were made. In one cavity MTA was placed, in another Portland Cement type I and the third remained empty. The experimental groups were sacrificed at the 1st, 2nd, 3rd and 4th respective weeks and evaluated histologically by counting osteocytes and osteoblasts.

Results:

Both MTA and Portland cement have the same osteoinductive capacity in the 1st, 2nd and 3rd week (0.05 MTA had greater osteoinductive capacity by stimulating a greater number of osteoblasts than the Portland Cement (p = 0.024).

Conclusions:

The MTA and Portland cement type I showed a similar osteoinductive effect during the first 3 weeks of evaluation, however, MTA had the greatest osteoinductive effect during the fourth week of evaluation.

Full text: Available Collection: International databases Database: LILACS Language: Spanish Journal: Odontol. vital Journal subject: Odontologia Year: 2016 Document type: Article
Full text: Available Collection: International databases Database: LILACS Language: Spanish Journal: Odontol. vital Journal subject: Odontologia Year: 2016 Document type: Article
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