Peak nasal inspiratory flow in children and adolescents with sickle cell disease: a case-control study
Rev. Assoc. Med. Bras. (1992, Impr.)
; 69(10): e20210819, 2023. tab
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1514690
Responsible library:
BR1.1
ABSTRACT
SUMMARY OBJECTIVE:
Sickle cell disease is the most frequent of the hereditary hemoglobinopathies and it presents multisystemic effects. A manifestation that is commonly found in sickle cell disease is upper airway obstruction, particularly adenotonsillar hypertrophy. This study aims to evaluate the peak nasal inspiratory flow measurements of children and adolescents with sickle cell disease.METHODS:
This is a case-control study on children aged between 8 and 15 years who were diagnosed with sickle cell disease. Peak nasal inspiratory flow measurements were obtained from patients.RESULTS:
A total of 279 patients were enrolled in this study, with 93 in the case group and 186 in the control group. The case group had an 82.83% chance of having lower peak nasal inspiratory flow values than the control group. In the case group, 75% of the peak nasal inspiratory flow values were in the lower standards, whereas in the control group, only 25% were in the lower standards.CONCLUSION:
This study showed a high prevalence of reduced peak nasal inspiratory flow values in children with sickle cell disease and could certainly be incorporated into the day-to-day clinical evaluation of patients as a screening instrument.
Full text:
Available
Collection:
International databases
Health context:
Sustainable Health Agenda for the Americas
Health problem:
Goal 10: Communicable diseases
Database:
LILACS
Language:
English
Journal:
Rev. Assoc. Med. Bras. (1992, Impr.)
Journal subject:
EducaÆo em Sa£de
/
GestÆo do Conhecimento para a Pesquisa em Sa£de
/
Medicine
Year:
2023
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Hemominas Foundation/BR
/
Pontifícia Universidade Católica de Minas Gerais/BR
/
Universidade Federal de Minas Gerais/BR