Human papillomavirus prevalence and genotype distribution among young women and men in Maputo city, Mozambique
BMJ Open
; 7(7): 1-14, 2017. Ilus, Graf, Tab
Article
in English
| RSDM
| ID: biblio-1525648
Responsible library:
MZ1.1
ABSTRACT
Objectives:
Human papillomavirus (HPV) is a well-known cause of cervical cancer, the second most frequent cancer in female African populations. This study aimed at determining the prevalence of HPV infections and the genotype distribution in young adults aged 18-24, in Maputo city, Mozambique, and to assess the suitability of commercially available HPV vaccines.Methods:
This cross-sectional study was conducted between 2009 and 2011 at a youth clinic in Maputo Central Hospital. Cervical and urethral samples were obtained from 236 women and 176 men, respectively. Demographic and behavioural data were collected using structured questionnaires. HPV genotyping was performed for 35 different high, probably or possibly high-risk and low-risk HPV types using the CLART Human Papillomavirus 2.Results:
HPV prevalence was 168/412 (40.8%; 95% CI 36.0 to 45.5) and was significantly higher in women than in men (63.6%vs10.2%). HPV52 was the most frequent type found in women, followed by HPV35, -16,-53, -58,-6 and -51
Full text:
Available
Collection:
National databases
/
MZ
Database:
RSDM
Main subject:
Papillomaviridae
/
Papillomavirus Infections
/
Papillomavirus Vaccines
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
English
Journal:
BMJ Open
Year:
2017
Document type:
Article
Institution/Affiliation country:
Eduardo Mondlane University/MZ
/
Instituto Nacional de Saúde/MZ
/
Karolinska Institutet, Department of Laboratory Medicine, Division of Clinical Microbiology/SE
/
Karolinska Institutet, Department of Oncology-Pathology/SE
/
Public Health Agency of Sweden, Stockholm, Department of Microbiology/SE
/
Örebro University, Faculty of Medicine and Health, Department of Laboratory Medicine/SE