Antimicrobial resistance of Vibrio cholerae O1 serotype Ogawa isolated in Manhic¸a District Hospital, southern Mozambique
J. antimicrob. chemother
; 60(3): 662-664, 2007. Tab
Article
in English
| RSDM
| ID: biblio-1526781
Responsible library:
MZ1.1
ABSTRACT
Since the seventh pandemic caused by Vibrio cholerae biotype El Tor began in Indonesia in 1961, most regions of the world continue to report cholera outbreaks.1 Cholera is most common in rural areas or communities where sanitation conditions and water supply are problematic.2 In 1997, a cholera epidemic affected most countries of eastern, central and southern parts of Africa, including Mozambique. Nearly 80% of cases reported worldwide to WHO were from Africa ( 118 000 cases), and Africa had the highest case fatality rate, 4.9%, compared with 1.3% in the Americas and 1.7% in Asia.1 In Mozambique the epidemic started in August 1997, reaching an estimated 9000 cases and 259 deaths.1 Cholera continues to be endemic in Mozambique, concentrated mainly in Beira and Maputo cities, with many cases occurring during the rainy season.3 In many African countries, V. cholerae O1 serotype Ogawa has been the strain most frequently isolated and associated with cholera outbreaks.46 As with many other diarrhoeal diseases, cholera can be managed by re-hydration alone, but antimicrobial therapy can help to shorten the course of disease and to break the transmissibility cycle during epidemics. Antimicrobial therapy is also recommended for severe or chronic cases of diar rhoea. However, the increase in antimicrobial-resistant strains of bacteria causing diarrhoeal disease is concerning, especially in developing countries.7,8 Tetracycline derivatives are the first-line drug for cholera treatment in many of these countries, however, V. cholerae strains resistant to this antimicrobial and others, including ciprofloxacin, have been reported.8 In rural areas of Mozambique, data on antimicrobial resistance are scarce, par ticularly for V. cholerae strains
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Collection:
National databases
/
MZ
Health context:
SDG3 - Health and Well-Being
/
Neglected Diseases
/
SDG3 - Target 3.3 End transmission of communicable diseases
Health problem:
Target 3.3: End transmission of communicable diseases
/
Target 3.9: Reduce the amount of deaths produced by dangerous chemicals and the pollution of the air, water and soil
/
Cholera
/
Diarrhea
/
Neglected Diseases
/
Antimicrobial Resistance
/
Cholera
/
Diarrhoeal Infections
Database:
RSDM
Main subject:
Cholera
/
Vibrio cholerae O1
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
Africa
Language:
English
Journal:
J. antimicrob. chemother
Year:
2007
Document type:
Article
Institution/Affiliation country:
Idibaps, universitat de barcelona+ES
/
Centro de investigacão em saúde da manhiça (cism)/MZ
/
centro de investigacão em saúde da manhiça (cism)/MZ