Diabetes among women with preterm births: outcomes of a Brazilian multicenter study
Einstein (Säo Paulo)
; 21: eAO0515, 2023. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1528561
Responsible library:
BR1.1
ABSTRACT
ABSTRACT Objective The objective was to compare the maternal and perinatal characteristics and outcomes between women with and without diabetes in a Brazilian cohort of women with preterm births. Methods This was an ancillary analysis of the Brazilian Multicenter Study on Preterm Birth, which included 4,150 preterm births. This analysis divided preterm births into two groups according to the presence of diabetes; pregestational and gestational diabetes were clustered in the same Diabetes Group. Differences between both groups were assessed using χ 2 or Student's t tests. Results Preterm births of 133 and 4,017 women with and without diabetes, respectively, were included. The prevalence of diabetes was 3.2%. Pregnant women aged ≥35 years were more common in the Diabetes Group (31.6% versus 14.0% non-diabetic women, respectively). The rate of cesarean section among patients with diabetes was 68.2% versus 52.3% in non-diabetic cases), with a gestational age at birth between 34 and 36 weeks in 78.9% of the cases and 62.1% of the controls. Large-for-gestational-age babies were 7 times more common in the Diabetes Group. Conclusion Preterm birth among Brazilian women with diabetes was more than twice as prevalent; these women were older and had regular late preterm deliveries, usually by cesarean section. They also had a greater frequency of fetal morbidities, such as malformations and polyhydramnios, and a higher proportion of large-for-gestational-age and macrosomic neonates.
Full text:
Available
Collection:
International databases
Health context:
SDG3 - Health and Well-Being
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SDG3 - Target 3.1 Reduce Maternal Mortality
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SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5
Health problem:
Target 3.1: Reduce maternal mortality
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Target 3.2: Reduce avoidable death in newborns and children under 5
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Hypertension, Pregnancy-Induced
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Neonatal Healthcare
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Noncommunicable Diseases
Database:
LILACS
Type of study:
Controlled clinical trial
/
Risk factors
Country/Region as subject:
South America
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Brazil
Language:
English
Journal:
Einstein (Säo Paulo)
Journal subject:
Medicine
Year:
2023
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Campinas/BR