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Principais motivos de descarte de córneas para transplante na Paraíba: por que o anti-HBc merece atenção?* / Main reasons for discarding corneas for transplant in Paraíba: why does anti-HBc deserve attention?*
Alves, Esther Rocha de Queiroz; Carvalho, Lara Fernandes de; Diniz, Camila Melo Gadelha Pereira.
Affiliation
  • Alves, Esther Rocha de Queiroz; Centro Universitário de João Pessoa. João Pessoa. BR
  • Carvalho, Lara Fernandes de; Centro Universitário de João Pessoa. João Pessoa. BR
  • Diniz, Camila Melo Gadelha Pereira; Centro Universitário de João Pessoa. João Pessoa. BR
Rev. bras. oftalmol ; 83: e0003, 2024. tab, graf
Article in Portuguese | LILACS | ID: biblio-1529931
Responsible library: BR1.2
RESUMO
RESUMO

Objetivo:

Identificar o perfil dos doadores de tecidos oculares humanos na área de atuação do Banco de Olhos da Paraíba, destacando o impacto da sorologia positiva para hepatite B no descarte dos tecidos para transplante.

Métodos:

O estudo é transversal e utilizou dados do Banco de Olhos da Paraíba entre janeiro de 2013 e dezembro de 2022. Dados sobre procedência, idade, sexo, causa do óbito, tempo entre óbito e enucleação, resultados sorológicos e motivo de descarte das córneas dos doadores foram coletados.

Resultados:

O maior motivo de descarte foi por sorologia positiva (56,5%), sendo positivadas as sorologias positivas para hepatite B e HBsAg em 11,1% e 4,75% dos pacientes, respectivamente.

Conclusão:

A sorologia positiva para hepatite B como um critério de descarte absoluto é responsável por grande parcela de descartes, apesar da pouca informação sobre suas repercussões e representação de infectividade nos receptores do transplante.
ABSTRACT
ABSTRACT

Objective:

To identify the profile of human ocular tissue donors in the area covered by the Eye Bank of Paraíba (PB), highlighting the impact of positive serology for hepatitis B (anti-HBc) in the disposal of tissues for transplantation.

Methods:

This is a cross-sectional that uses data from the Eye Bank of Paraíba (PB) between January 2013 and December 2022. Data on origin, age, sex, cause of death, time between death and enucleation, serological results, and reason for discarded donor corneas were collected.

Results:

The main reason for discarding was due to positive serology (56.5%), with positive anti-HBc and HBsAg serology in 11.1% and 4.75% of patients, respectively.

Conclusion:

Anti-HBc positive serology as an absolute disposal criterion is responsible for great part of disposals, despite little information about its repercussions and representation of infectivity in transplant recipients.
Subject(s)


Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Goal 10: Communicable diseases / Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Hepatitis / Digestive System Diseases / Infections Database: LILACS Main subject: Tissue Donors / Corneal Transplantation / Donor Selection / Eye Banks / Hepatitis B Antibodies Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged, 80 and over / Child / Child, preschool / Female / Humans / Male Language: Portuguese Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2024 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Centro Universitário de João Pessoa/BR

Full text: Available Collection: International databases Health context: Sustainable Health Agenda for the Americas / SDG3 - Health and Well-Being / SDG3 - Target 3.3 End transmission of communicable diseases / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 - Target 3.2 Reduce avoidable death in newborns and children under 5 Health problem: Goal 10: Communicable diseases / Target 3.3: End transmission of communicable diseases / Target 3.2: Reduce avoidable death in newborns and children under 5 / Hepatitis / Digestive System Diseases / Infections Database: LILACS Main subject: Tissue Donors / Corneal Transplantation / Donor Selection / Eye Banks / Hepatitis B Antibodies Type of study: Diagnostic study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Adult / Aged / Aged, 80 and over / Child / Child, preschool / Female / Humans / Male Language: Portuguese Journal: Rev. bras. oftalmol Journal subject: Ophthalmology Year: 2024 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Centro Universitário de João Pessoa/BR
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