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Thrombosis of the vasa vasorum of the large and medium size pulmonary artery and vein leads to pulmonary thromboembolism in COVID-19
Daisley, Hubert; Acco, Oneka; Daisley, Martina; George, Dennecia; Paul, Lilly; James, Errol; Rampersad, Arlene; Narinesingh, Farhaana; Humphrey, Ornella; Daisley, Johann; Nathan, Melissa.
Affiliation
  • Daisley, Hubert; General Hospital. San Fernando. TT
  • Acco, Oneka; The University of the West Indies. Mona. JM
  • Daisley, Martina; Princess Alexandra Hospital. The Valley. AI
  • George, Dennecia; Scarborough General Hospital. Signal Hill. TT
  • Paul, Lilly; The University of the West Indies. Mona. JM
  • James, Errol; Beacon Plastic and Cosmetic Surgery. Woodbrook. TT
  • Rampersad, Arlene; General Hospital. San Fernando. TT
  • Narinesingh, Farhaana; General Hospital. San Fernando. TT
  • Humphrey, Ornella; General Hospital. San Fernando. TT
  • Daisley, Johann; Scarborough General Hospital. Signal Hill. TT
  • Nathan, Melissa; The University of the West Indies. St Augustine. TT
Autops. Case Rep ; 14: e2024491, 2024. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1557157
Responsible library: BR1.1
ABSTRACT
ABSTRACT The vasa vasorum of the large pulmonary vessels is involved in the pathology of COVID-19. This specialized microvasculature plays a major role in the biology and pathology of the pulmonary vessel walls. We have evidence that thrombosis of the vasa vasorum of the large and medium-sized pulmonary vessels during severe COVID-19 causes ischemia and subsequent death of the pulmonary vasculature endothelium. Subsequent release of thrombi from the vasa interna into the pulmonary circulation and pulmonary embolism generated at the ischemic pulmonary vascular endothelium site, are the central pathophysiological mechanisms in COVID-19 responsible for pulmonary thromboembolism. The thrombosis of the vasa vasorum of the large and medium-sized pulmonary vessels is an internal event leading to pulmonary thromboembolism in COVID-19.


Full text: Available Collection: International databases Database: LILACS Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2024 Document type: Article Affiliation country: Jamaica / Trinidad and Tobago Institution/Affiliation country: Beacon Plastic and Cosmetic Surgery/TT / General Hospital/TT / Princess Alexandra Hospital/AI / Scarborough General Hospital/TT / The University of the West Indies/JM / The University of the West Indies/TT

Full text: Available Collection: International databases Database: LILACS Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2024 Document type: Article Affiliation country: Jamaica / Trinidad and Tobago Institution/Affiliation country: Beacon Plastic and Cosmetic Surgery/TT / General Hospital/TT / Princess Alexandra Hospital/AI / Scarborough General Hospital/TT / The University of the West Indies/JM / The University of the West Indies/TT
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