Structural diversity and biological importance of ABO, H, Lewis and secretor histo-blood group carbohydrates
Rev. bras. hematol. hemoter
; 38(4): 331-340, Oct.-Dec. 2016. tab, graf
Article
in English
| LILACS
| ID: biblio-829941
Responsible library:
BR1.1
Localization: BR408.1
ABSTRACT
ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
ABO Blood-Group System
/
Lewis Blood Group Antigens
Language:
English
Journal:
Rev. bras. hematol. hemoter
Journal subject:
Hematology
Year:
2016
Document type:
Article
/
Project document
Affiliation country:
Brazil
Institution/Affiliation country:
Faculdade de Medicina de São José do Rio Preto/BR