Neuromielitis óptica y lupus eritematoso sistémico en un hombre: caso clínico / Neuromyelitis optica presenting concomitantly with systemic lupus erythematosus: report of one case
Rev. méd. Chile
; 144(9): 1226-1229, set. 2016. ilus
Article
in Spanish
| LILACS
| ID: biblio-830633
Responsible library:
CL1.1
ABSTRACT
Neuromyelitis optica (NMO) is a severe demyelinating disease of the central nervous system, which preferentially attacks the optic nerve and spinal cord. It is associated with antibodies against aquaporin 4. Morbidity and mortality are higher than in multiple sclerosis and its treatment focuses on immunosuppressive drugs. Immunomodulators are contraindicated. We report a previously healthy 35-year-old man, presenting with NMO concomitantly with systemic lupus erythematosus. His evolution was torpid with three outbreaks in the 10 months after the diagnosis, requiring a first-line therapy with methylprednisolone and cyclophosphamide and then a second-line therapy with rituximab.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Neuromyelitis Optica
/
Lupus Erythematosus, Systemic
Limits:
Adult
/
Humans
/
Male
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2016
Document type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Base de Osorno/CL