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Frecuencia de anticuerpos anti-transglutaminasa y antiendomisio en pacientes con diabetes tipo 1 / Association of type 1 diabetes mellitus with celiac disease
Lillo G., Macarena; Saavedra B., Giannina; Concha C., Francisca; Ávila A., Alejandra; Codner D., Ethel; Araya Q., Magdalena; Oyarzún A., Amaya; Pérez B., Francisco.
Affiliation
  • Lillo G., Macarena; Universidad de Chile. Facultad de Medicina. Departamento de Nutrición. Laboratorio de Nutrigenómica. CL
  • Saavedra B., Giannina; Universidad de Chile. Facultad de Medicina. Departamento de Nutrición. Laboratorio de Nutrigenómica. CL
  • Concha C., Francisca; Universidad de Chile. Facultad de Medicina. Departamento de Nutrición. Laboratorio de Nutrigenómica. CL
  • Ávila A., Alejandra; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil (IDIMI). CL
  • Codner D., Ethel; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil (IDIMI). CL
  • Araya Q., Magdalena; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil (IDIMI). CL
  • Oyarzún A., Amaya; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil (IDIMI). CL
  • Pérez B., Francisco; Universidad de Chile. Facultad de Medicina. Departamento de Nutrición. Laboratorio de Nutrigenómica. CL
Rev. chil. endocrinol. diabetes ; 9(1): 15-18, ene. 2016. tab
Article in Spanish | LILACS | ID: biblio-831338
Responsible library: CL1.1
ABSTRACT

Background:

Type 1 diabetes mellitus and celiac disease share common genetic and immunological aspects and celiac disease is more common among type 1 diabetic patients.

Aim:

To determine the frequency of anti endomysial and anti transglutaminase antibodies among patients with type 1 diabetes. Material and

Methods:

Anti endomysialantibodies determined by indirect immunofluorescence an anti transglutaminase antibodies determined by ELISA were measured in 410 serum samples of patients with type 1 diabetes.

Results:

Seventy one samples (17 percent) had positive anti transglutaminase antibodies. Among these, 17 had also positive anti endomysial antibodies. In 11 of these 17 patients, the presence of celiac disease was confirmed.

Conclusions:

Among patients with type 1 diabetes mellitus, the frequency of celiac disease is three times higher than in the general population.
Subject(s)

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Full text: Available Collection: International databases Database: LILACS Main subject: Celiac Disease / Diabetes Mellitus, Type 1 Type of study: Risk factors Limits: Adolescent / Child / Female / Humans / Male Language: Spanish Journal: Rev. chil. endocrinol. diabetes Journal subject: Endocrinology Year: 2016 Document type: Article / Project document Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL
Fulltext
Add to My VHL
Print
XML
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Full text: Available Collection: International databases Database: LILACS Main subject: Celiac Disease / Diabetes Mellitus, Type 1 Type of study: Risk factors Limits: Adolescent / Child / Female / Humans / Male Language: Spanish Journal: Rev. chil. endocrinol. diabetes Journal subject: Endocrinology Year: 2016 Document type: Article / Project document Affiliation country: Chile Institution/Affiliation country: Universidad de Chile/CL