Anatomo-radiological correlation using 18-FDG-PET in abdominal sepsis model in rats. A preliminary study
Acta cir. bras
; 32(3): 175-181, Mar. 2017. graf
Article
in English
| LILACS
| ID: biblio-837692
Responsible library:
BR1.1
ABSTRACT
Abstract Purpose:
To examine a correlation of micro-PET images with photographic images of the digestive organs in abdominal sepsis model.Methods:
Male Wistar rats weighing 265±18g were used. Abdominal sepsis was induced by ligature and cecal puncture. Micro-PET Images from abdominal cavity septic foci were obtained using 18-Fluoro-deoxyglucose, looking for a correlation with photographic images of abdominal cavity organs. Pearson's correlation test was used.Results:
The mean standard uptake values (SUV) and lesion areas were 2.58±0.63SUVbwg/ml and 546.87±300.95mm2, respectively. There was a strong positive correlation between the two variables (r=0.863, p=0.137), which resulted in a coefficient of determination r2?0.75, meaning that 75% of SUV variation is explained by the lesion areas of digestive organs.Conclusion:
Micro-PET allows high throughput assessment of lesion count and volume in pre-clinical rat model of CPL abdominal sepsis.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Sepsis
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Positron-Emission Tomography
/
Intraabdominal Infections
Type of study:
Evaluation study
/
Prognostic study
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Federal do Rio Grande do Norte/BR