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Prescribing cascade: A proposed new way to evaluate it
Ponte, Marcelo L; Wachs, Lionel; Wachs, Adolfo; Serra, Héctor A.
Affiliation
  • Ponte, Marcelo L; Hospital General de Agudos Dr. Cosme Argerich. AR
  • Wachs, Lionel; Hospital General de Agudos Dr. Cosme Argerich. AR
  • Wachs, Adolfo; Hospital General de Agudos Dr. Cosme Argerich. AR
  • Serra, Héctor A; Hospital General de Agudos Dr. Cosme Argerich. AR
Medicina (B.Aires) ; 77(1): 13-16, feb. 2017. tab
Article in English | LILACS | ID: biblio-841626
Responsible library: BR1.1
ABSTRACT
Prescribing cascade is defined as the situation in which a first drug administered to a patient causes adverse event signs and symptoms, that are misinterpreted as a new condition, resulting in a new medication being prescribed. The cascade may have multiple steps and differ in complexity and severity. Despite being well identified, prescribing cascade is an increasingly common problem in medical practice. It constitutes a warning about irrational use of medicines that puts health at risk and increases treatment costs if it is not taken into account. In this article, representative cases taken from Hospital General de Agudos Dr. Cosme Argerich pharmacovigilance database were selected to assess a proper score and an algorithm that define the probable prescribing cascade.
RESUMEN
La prescripción en cascada identifica la situación generada tras la administración a un paciente de un medicamento que le provoca un evento adverso, el cual al no ser debidamente reconocido como tal por el profesional desencadena nuevas prescripciones farmacológicas que pueden agravar o generar nuevos eventos adversos. Por ello, de acuerdo a la idiosincrasia de cada paciente, la cascada puede tener múltiples pasos y diferir en complejidad y gravedad. A pesar de estar identificada, la prescripción en cascada es un problema cada vez más común en la práctica médica y una advertencia sobre el uso irracional de los medicamentos que pone en riesgo la salud e incrementa sus costos si no se tiene en cuenta. En este artículo, se seleccionaron casos representativos tomados de la base de datos de farmacovigilancia del Hospital General de Agudos Dr. Cosme Argerich para probar un nuevo score y un algoritmo de decisión, que evalúen la supuesta cascada prescriptiva.
Subject(s)

Full text: Available Collection: International databases Database: LILACS Main subject: Drug Prescriptions / Practice Patterns, Physicians' / Polypharmacy / Drug-Related Side Effects and Adverse Reactions Type of study: Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2017 Document type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital General de Agudos Dr. Cosme Argerich/AR
Full text: Available Collection: International databases Database: LILACS Main subject: Drug Prescriptions / Practice Patterns, Physicians' / Polypharmacy / Drug-Related Side Effects and Adverse Reactions Type of study: Prognostic study Limits: Adult / Aged / Female / Humans / Male Language: English Journal: Medicina (B.Aires) Journal subject: Medicine Year: 2017 Document type: Article Affiliation country: Argentina Institution/Affiliation country: Hospital General de Agudos Dr. Cosme Argerich/AR
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