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La triyodotironina en la medicina clínica
Werner, Sidney C.
Affiliation
  • Werner, Sidney C; Columbia University. Department of Medicine.
Rev. argent. endocrinol. metab ; Rev. argent. endocrinol. metab;52(2): 53-56, jul. 2015. ilus
Article in Es | LILACS | ID: biblio-843115
Responsible library: AR1.2
RESUMEN
Aparte de la importancia para el fisiólogo, la triyodotironina es de valor para el clínico. Uno de sus usos es en el diagnóstico del hipertiroidismo y en descubrir el bocio nodular no tóxico con nódulos activos. Otro uso es en el tratamiento del hipotiroidismo. Se han sugerido otras indicaciones, pero no se ha confirmado aún su eficacia. Se han comunicado tratamientos con éxito de pacientes hipotiroideos resistentes que no respondieron a la administración oral de tiroides desecada. Se ha sostenido que algunos casos de oligozoospermia masculina han mejorado consecutivamente a la administración del triyodotiroinina. Finalmente, se ha hecho aumentar el metabolismo basal en algunos pacientes con metabolismo disminuido pero sin hipotiroidismo. Estos resultados, sin embargo, requieren una evaluación crítica severa por medio del estudio de gran número de pacientes a los que se les administre la hormona y una sustancia testigo antes de que puedan admitirse en la práctica.
ABSTRACT
Apart from its importance to the physiologist, triio­dothyroine has been of value to the clinician. One use has been in the diagnosis of hyperthyroidism and in the detection of nontoxic nodular goiter with "bot" or active nodules. Another has been in the treatment of hypothyroidism. Further indications have been suggested but efficacy has not yet been confirmed. Claims have been made for the successful treatment of resistant hypothyroid patients who did not respond to desiccated thyroid by mouth. Some instances of male oligozzospermia have been said to improve following triiodothyronine administration. Finally the basal metabolic rate has been made to increase in some patients with hypometabolism but without hypothyroidism. However, such claims require very critical appraisal by means of large series of patients receiving both hormone and a placebo, before they can be admitted into practice.
Full text: 1 Collection: 01-internacional Database: LILACS Type of study: Clinical_trials Language: Es Journal: Rev. argent. endocrinol. metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2015 Document type: Article Affiliation country: United States Country of publication: Argentina
Full text: 1 Collection: 01-internacional Database: LILACS Type of study: Clinical_trials Language: Es Journal: Rev. argent. endocrinol. metab Journal subject: ENDOCRINOLOGIA / METABOLISMO Year: 2015 Document type: Article Affiliation country: United States Country of publication: Argentina