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Mortalidade por cirrose, câncer hepático e transtornos devidos ao uso de álcool: Carga Global de Doenças no Brasil, 1990 e 2015 / Mortality due to cirrhosis, liver cancer, and disorders attributed to alcohol use: Global Burden of Disease in Brazil, 1990 and 2015
Melo, Ana Paula Souto; França, Elisabeth Barboza; Malta, Deborah Carvalho; Garcia, Leila Posenato; Mooney, Meghan; Naghavi, Mohsen.
Affiliation
  • Melo, Ana Paula Souto; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
  • França, Elisabeth Barboza; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
  • Malta, Deborah Carvalho; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
  • Garcia, Leila Posenato; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
  • Mooney, Meghan; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
  • Naghavi, Mohsen; Universidade Federal de São João Del-Rei. Faculdade de Medicina. Divinópolis. BR
Rev. bras. epidemiol ; 20(supl.1): 61-74, Mai. 2017. tab, graf
Article in Portuguese | LILACS | ID: biblio-843751
Responsible library: BR1.1
RESUMO
RESUMO

Introdução:

O uso de álcool é um dos principais fatores de risco preveníveis para mortalidade ou incapacidade prematuras.

Objetivo:

Descrever as estimativas de mortalidade e anos de vida perdidos por morte prematura (YLL) por cirrose, câncer hepático e transtornos devidos ao uso de álcool no Brasil e suas unidades da federação (UFs), em 1990 e 2015.

Métodos:

Estudo descritivo com dados do estudo de Carga Global de Doenças (2015) e do Sistema de Informações sobre Mortalidade (SIM). Modelos estatísticos foram empregados para obter estimativas corrigidas de mortalidade pelas causas selecionadas. As taxas de mortalidade foram padronizadas por idade (TMPI).

Resultados:

Em 1990, foram estimados 16.226 óbitos para as 3 condições (17,0/100 mil habitantes), enquanto em 2015 foram 28.337 (15,7/100 mil habitantes). Houve redução da mortalidade (por 100 mil habitantes) por cirrose (de 11,4 para 9,5) e estabilidade por câncer hepático (1,5 e 1,9) e transtornos devidos ao uso de álcool (4,1 e 4,3). As TMPI foram 5,1 vezes maiores entre os homens, e as 5 UFs com maiores TMPI e YLL foram da Região Nordeste Sergipe, Ceará, Pernambuco, Paraíba e Alagoas. As taxas de mortalidade e de YLL pelas três condições estudadas ascenderam no ranking das causas de óbito, em ambos os sexos, exceto a cirrose no feminino.

Conclusão:

As três condições estudadas são responsáveis por importante carga de mortalidade prematura no Brasil, principalmente entre homens e residentes na região nordeste. Esses resultados reforçam a necessidade de políticas públicas para o enfrentamento ao consumo nocivo do álcool no Brasil.
ABSTRACT
ABSTRACT

Introduction:

Alcohol use is one of the main preventable risk factors affecting mortality and premature disability.

Objective:

To describe the estimates of mortality and years of life lost as a result of premature death (YLL) due to cirrhosis, liver cancer, and disorders attributed to alcohol use in Brazil and its federated units in 1990 and 2015.

Methods:

Descriptive study using data from the Global Burden of Disease Study (2015) and the Mortality Information System (SIM). Statistical models were used to obtain corrected mortality estimates for selected causes. Rates were standardized by age.

Results:

In 1990, 16,226 deaths were estimated for the three conditions (17.0/100 thousand inhabitants), while in 2015 there were 28,337 deaths (15.7/100 thousand inhabitants). There was a reduction in mortality (per 100 thousand) due to cirrhosis (from 11.4 to 9.5), stability in mortality rates related to liver cancer (1.5 and 1.9), and stability in mortality rates caused by alcohol use disorders (4.1 and 4.3). Mortality rates were 5.1 times higher among men, and the five states with the highest mortality rates and YLL were from the Northeast Region Sergipe, Ceará, Pernambuco, Paraíba, and Alagoas. Mortality and YLL rates for the three conditions studied increased in the ranking of causes of death in both sexes, with the exception of cirrhosis in the female population.

Conclusion:

The three conditions studied are responsible for a significant burden of premature mortality in Brazil, especially among men and residents of the northeast region. These results reinforce the urgent need for public policies that address harmful alcohol consumption in Brazil.
Subject(s)


Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Target 3.4: Reduce premature mortality due to noncommunicable diseases / Target 3.5: Prevention and treatment of consumption of psychoactive substances / Cirrhosis / Digestive System Diseases / Liver Cancer / Alcohol Database: LILACS Main subject: Alcohol-Related Disorders / Global Burden of Disease / Liver Cirrhosis / Liver Neoplasms Type of study: Prognostic study / Risk factors Aspects: Patient-preference Limits: Adolescent / Adult / Aged / Aged, 80 and over / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. bras. epidemiol Journal subject: Epidemiology / Public Health Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São João Del-Rei/BR

Full text: Available Collection: International databases Health context: SDG3 - Health and Well-Being / SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases / SDG3 -Target 3.5 Prevention and treatment of consumption of psychoactive substances Health problem: Target 3.4: Reduce premature mortality due to noncommunicable diseases / Target 3.5: Prevention and treatment of consumption of psychoactive substances / Cirrhosis / Digestive System Diseases / Liver Cancer / Alcohol Database: LILACS Main subject: Alcohol-Related Disorders / Global Burden of Disease / Liver Cirrhosis / Liver Neoplasms Type of study: Prognostic study / Risk factors Aspects: Patient-preference Limits: Adolescent / Adult / Aged / Aged, 80 and over / Female / Humans / Male Country/Region as subject: South America / Brazil Language: Portuguese Journal: Rev. bras. epidemiol Journal subject: Epidemiology / Public Health Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São João Del-Rei/BR
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