Prenatal diagnosis of thalidomide syndrome / Diagnóstico prenatal do síndrome da talidomida

ABSTRACT

A case of thalidomide syndrome diagnosed by ultrasound in the 17th weeck of pregnancy is presented. The pregnant woman had leprosy and received adjuvant treatment with thalidomide. The affected fetus was exposed to the drug until the 35th day of pregnancy and presented absent external ears, upper limb phocomelia and absent tibiae and fibulae. No internal organ abnormalities were noticed at autopsy