Histopathological differences between genders in patients with oral squamous cell carcinoma
Clin. biomed. res
; 37(3): 147-150, 2017. tab
Article
in English
| LILACS
| ID: biblio-859740
Responsible library:
BR18.1
Localization: BR18.1
ABSTRACT
Introduction:
Oral cancer ranks fifth among the most frequent malignant tumors in men in Brazil. The incidence of this tumor among women has grown. It is still controversial whether gender can influence the outcome or the prognostic features of the disease.Objectives:
To compare the histopathological features of oral squamous cell carcinomas between genders among patients undergoing surgical treatment in an oncological hospital of southern Brazil.Methods:
Between 2007 and 2011, 404 patients underwent resection of malignant tumors of the oral cavity in the head and neck department of this institution. A subgroup of 209 previously untreated oral cavity squamous cell carcinoma cases was selected for comparative analysis.Results:
In total, 68 participants were women and 141 were men. The tongue was the most common subsite in both genders. Men presented lower mean age and women presented tumors with smaller depth of invasion. Although among women it was observed a trend towards tumors with less aggressive characteristics, no other variable showed statistically significance.Conclusion:
Women with oral tumors tend to present more superficial primary tumors and at a later age (AU)
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Mouth Neoplasms
/
Carcinoma, Squamous Cell
/
Sex Factors
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Clin. biomed. res
Journal subject:
Medicine
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa Hospital Complex/BR
/
Universidade de Santa Cruz do Sul/BR