Sublingual immunotherapy in the treatment of allergic asthma: a systematic review with meta-analysis
Clin. biomed. res
; 37(4): 334-340, 2017. ilus, tab, graf
Article
in English
| LILACS
| ID: biblio-876759
Responsible library:
BR18.1
ABSTRACT
Introduction:
The guidelines for the management of allergic respiratory diseases oriented towards control from medical treatment combined with measures of environmental hygiene. Immunotherapy is one of several types of treatment, applied in combination with prophylactic drugs and environmental care. The aim of the study is to evaluate the efficacy of sublingual immunotherapy (SLIT) for house dust mites (HDM) in people with allergic asthma.Methods:
The study is based on a systematic review with meta-analysis of randomized clinical trials, associating sublingual immunotherapy with the treatment of allergic patients with HDM.Results:
The searches were applied in PubMed, ScienceDirect and Scielo databases. Initially, 98 articles were recovered, of which only nine were eligible. Of these, eight (88.9%) were conducted in Europe and only one (11.1%) in Asia. Comparing the outcomes expiratory volume in the first minute (FEV1 ) and sensitivity to allergens (HDM) between SLIT and placebo groups before and after intervention, no differences were observed between the groups.Conclusions:
SLIT is not evidenced significantly by meta-analysis for the treatment of allergic asthma (AU)
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Asthma
/
Sublingual Immunotherapy
/
Rhinitis, Allergic
Type of study:
Controlled clinical trial
/
Practice guideline
/
Systematic review
Limits:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clin. biomed. res
Journal subject:
Medicine
Year:
2017
Document type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro Universitário da Serra Gaúcha/BR
/
Pontifícia Universidade Católica do Rio Grande do Sul/BR