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Micrornas and current concepts on the pathogenesis of abdominal aortic aneurysm
Joviliano, Edwaldo Edner; Ribeiro, Mauricio Serra; Tenorio, Emanuel Junior Ramos.
Affiliation
  • Joviliano, Edwaldo Edner; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Ribeiro, Mauricio Serra; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
  • Tenorio, Emanuel Junior Ramos; Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Department of Surgery and Anatomy. Ribeirão Preto. BR
Rev. bras. cir. cardiovasc ; 32(3): 215-224, May-June 2017. tab, graf
Article in English | LILACS | ID: biblio-897914
Responsible library: BR1.1
ABSTRACT
Abstract

Objective:

Abdominal aortic aneurysm is an important cause of morbidity and mortality in the elderly. Currently, the only way to prevent rupture and death related to abdominal aortic aneurysms is through surgical intervention. Endovascular treatment is associated with less morbidity than conventional treatment. The formation of an aneurysm is a complex multifactorial process, involving destructive remodeling of the connective tissue around the affected segment of the aorta wall. MicroRNAs are small sequences of non-coding RNAs that control diverse cellular functions by promoting degradation or inhibition of translation of specific mRNAs. A profile aberrant expression of miRNAs has been linked to human diseases, including cardiovascular dysfunction.
Subject(s)

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Full text: Available Collection: International databases Health context: SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases Health problem: Cardiovascular Disease Database: LILACS Main subject: Aorta, Abdominal / Aortic Aneurysm, Abdominal / MicroRNAs Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / CIRURGIA GERAL Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR
Fulltext
Add to My VHL
Print
XML
Search on Google

Full text: Available Collection: International databases Health context: SDG3 - Target 3.4 Reduce premature mortality due to noncommunicable diseases Health problem: Cardiovascular Disease Database: LILACS Main subject: Aorta, Abdominal / Aortic Aneurysm, Abdominal / MicroRNAs Type of study: Etiology study / Risk factors Limits: Humans Language: English Journal: Rev. bras. cir. cardiovasc Journal subject: Cardiology / CIRURGIA GERAL Year: 2017 Document type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade de São Paulo/BR