Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells reported in an asymptomatic patient: a rare case and literature review
Autops. Case Rep
; 7(4): 51-57, Oct.-Dec. 2017. ilus
Article
in English
| LILACS
| ID: biblio-905407
Responsible library:
BR26.7
ABSTRACT
Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (UC-OGC) is a rare and poorly described pancreatic malignancy. It is comprised of mononuclear, pleomorphic, and undifferentiated cells as well as osteoclast-like giant cells (OGC's). It constitutes less than 1% of pancreatic non-endocrine neoplasia and is twice as likely to occur in females as in males. Its histopathologic properties remain poorly understood. It is suspected that UC-OGC is of epithelial origin that can then transition to mesenchymal elements. As part of this study, we describe a case of a malignant pancreatic neoplasm that was discovered in a 69-year old patient as an incidental finding. We also provide an overview of previously published data to highlight UC-OGC's clinical and pathologic features.
Full text:
Available
Collection:
International databases
Database:
LILACS
Main subject:
Osteoclasts
/
Pancreatic Neoplasms
/
Carcinoma, Pancreatic Ductal
Limits:
Aged
/
Humans
/
Male
Language:
English
Journal:
Autops. Case Rep
Journal subject:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Year:
2017
Document type:
Article
Affiliation country:
United States
Institution/Affiliation country:
St. John Hospital and Medical Center/US
/
Vanderbilt University Medical Center/US